| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEZ61990.1 | hflB | HMPREF0762_00077 | HMPREF0762_00941 | SPFH/Band 7/PHB domain protein; KEGG: reh:H16_A2768 7.3e-26 predicted membrane-bound protease subunit K01423; Psort location: Cytoplasmic, score: 8.87. | ATP-dependent metallopeptidase HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.934 |
| EEZ62002.1 | hflB | HMPREF0762_00089 | HMPREF0762_00941 | SPFH/Band 7/PHB domain protein; KEGG: reh:H16_A2036 2.6e-14 membrane protease subunits, stomatin/prohibitin homologs K01423; Psort location: CytoplasmicMembrane, score: 9.75. | ATP-dependent metallopeptidase HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.925 |
| folP | hflB | HMPREF0762_00940 | HMPREF0762_00941 | Dihydropteroate synthase; KEGG: rso:RSc1527 1.6e-60 folP, RS03777; probable 7,8-dihydropteroate synthase protein K00796; Psort location: Cytoplasmic, score: 8.87. | ATP-dependent metallopeptidase HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.789 |
| folP | hpt | HMPREF0762_00940 | HMPREF0762_00942 | Dihydropteroate synthase; KEGG: rso:RSc1527 1.6e-60 folP, RS03777; probable 7,8-dihydropteroate synthase protein K00796; Psort location: Cytoplasmic, score: 8.87. | KEGG: mle:ML0214 2.8e-49 hpt; putative hypoxanthine phosphoribosyltransferase K00760; Psort location: Cytoplasmic, score: 9.98; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.442 |
| hflB | EEZ61990.1 | HMPREF0762_00941 | HMPREF0762_00077 | ATP-dependent metallopeptidase HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | SPFH/Band 7/PHB domain protein; KEGG: reh:H16_A2768 7.3e-26 predicted membrane-bound protease subunit K01423; Psort location: Cytoplasmic, score: 8.87. | 0.934 |
| hflB | EEZ62002.1 | HMPREF0762_00941 | HMPREF0762_00089 | ATP-dependent metallopeptidase HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | SPFH/Band 7/PHB domain protein; KEGG: reh:H16_A2036 2.6e-14 membrane protease subunits, stomatin/prohibitin homologs K01423; Psort location: CytoplasmicMembrane, score: 9.75. | 0.925 |
| hflB | folP | HMPREF0762_00941 | HMPREF0762_00940 | ATP-dependent metallopeptidase HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Dihydropteroate synthase; KEGG: rso:RSc1527 1.6e-60 folP, RS03777; probable 7,8-dihydropteroate synthase protein K00796; Psort location: Cytoplasmic, score: 8.87. | 0.789 |
| hflB | hpt | HMPREF0762_00941 | HMPREF0762_00942 | ATP-dependent metallopeptidase HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | KEGG: mle:ML0214 2.8e-49 hpt; putative hypoxanthine phosphoribosyltransferase K00760; Psort location: Cytoplasmic, score: 9.98; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.856 |
| hflB | rplC | HMPREF0762_00941 | HMPREF0762_00365 | ATP-dependent metallopeptidase HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.811 |
| hflB | rplO | HMPREF0762_00941 | HMPREF0762_01815 | ATP-dependent metallopeptidase HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.836 |
| hflB | rplQ | HMPREF0762_00941 | HMPREF0762_01918 | ATP-dependent metallopeptidase HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Ribosomal protein L17; KEGG: bpe:BP0475 0.00011 rne, ams, hmp1; ribonuclease E K08300; Belongs to the bacterial ribosomal protein bL17 family. | 0.797 |
| hflB | rplS | HMPREF0762_00941 | HMPREF0762_00266 | ATP-dependent metallopeptidase HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.821 |
| hflB | rpmA | HMPREF0762_00941 | HMPREF0762_00604 | ATP-dependent metallopeptidase HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family. | 0.801 |
| hflB | rpmJ | HMPREF0762_00941 | HMPREF0762_01923 | ATP-dependent metallopeptidase HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Ribosomal protein L36; Psort location: Extracellular, score: 8.82; Belongs to the bacterial ribosomal protein bL36 family. | 0.788 |
| hpt | folP | HMPREF0762_00942 | HMPREF0762_00940 | KEGG: mle:ML0214 2.8e-49 hpt; putative hypoxanthine phosphoribosyltransferase K00760; Psort location: Cytoplasmic, score: 9.98; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Dihydropteroate synthase; KEGG: rso:RSc1527 1.6e-60 folP, RS03777; probable 7,8-dihydropteroate synthase protein K00796; Psort location: Cytoplasmic, score: 8.87. | 0.442 |
| hpt | hflB | HMPREF0762_00942 | HMPREF0762_00941 | KEGG: mle:ML0214 2.8e-49 hpt; putative hypoxanthine phosphoribosyltransferase K00760; Psort location: Cytoplasmic, score: 9.98; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | ATP-dependent metallopeptidase HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.856 |
| rplC | hflB | HMPREF0762_00365 | HMPREF0762_00941 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | ATP-dependent metallopeptidase HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.811 |
| rplC | rplO | HMPREF0762_00365 | HMPREF0762_01815 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.998 |
| rplC | rplQ | HMPREF0762_00365 | HMPREF0762_01918 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | Ribosomal protein L17; KEGG: bpe:BP0475 0.00011 rne, ams, hmp1; ribonuclease E K08300; Belongs to the bacterial ribosomal protein bL17 family. | 0.981 |
| rplC | rplS | HMPREF0762_00365 | HMPREF0762_00266 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.979 |