STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (481 aa)    
Predicted Functional Partners:
purM
Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: hch:HCH_01906 2.4e-89 purM; phosphoribosylaminoimidazole (AIR) synthetase K01933; Psort location: Cytoplasmic, score: 8.87.
 
 0.998
purD
Phosphoribosylamine--glycine ligase; KEGG: bld:BLi00704 4.0e-105 purD; phosphoribosylglycinamide synthetase; RBL03738 K01945; Psort location: Cytoplasmic, score: 8.87; Belongs to the GARS family.
 
 0.996
EEZ60515.1
KEGG: blo:BL1108 0. purL; phosphoribosylformylglycinamidine synthase K01952; Psort location: Cytoplasmic, score: 8.87.
 
 0.993
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; KEGG: gme:Gmet_2905 1.3e-140 AICARFT/IMPCHase bienzyme:MGS-like K00602:K01492; Psort location: Cytoplasmic, score: 8.87.
 
 0.990
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
 
 0.990
purE
Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
 
 
 0.972
carB
KEGG: afu:AF1274 0. carB; carbamoyl-phosphate synthase large chain K01955; Psort location: Cytoplasmic, score: 8.87; Belongs to the CarB family.
  
 
 0.960
carA
KEGG: pca:Pcar_1613 9.0e-99 carbamoyl-phosphate synthase small subunit K01956; Psort location: Cytoplasmic, score: 8.87; Belongs to the CarA family.
  
 
 0.944
purC
KEGG: sfu:Sfum_1263 9.8e-86 phosphoribosylaminoimidazole-succinocarboxamide synthase K01923; Psort location: Cytoplasmic, score: 8.87; Belongs to the SAICAR synthetase family.
  
 0.940
prs
Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 0.920
Your Current Organism:
Slackia exigua
NCBI taxonomy Id: 649764
Other names: S. exigua ATCC 700122, Slackia exigua ATCC 700122, Slackia exigua str. ATCC 700122, Slackia exigua strain ATCC 700122
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