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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
htpGChaperone protein HtpG; Molecular chaperone. Has ATPase activity. (691 aa)    
Predicted Functional Partners:
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.998
EEZ62287.1
Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
 
 0.989
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
 
 0.942
EEZ62288.1
Tetratricopeptide repeat protein; KEGG: ava:Ava_1552 2.5e-07 serine/threonine protein kinase with TPR repeats K00908.
   
 0.938
EEZ60512.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
   
 0.938
EEZ61038.1
DnaJ domain protein; KEGG: cme:CMJ043C 0.00028 phycocyanobilin lyase alpha subunit K02288; Psort location: Cytoplasmic, score: 9.65.
  
 0.934
EEZ61118.1
DnaJ domain protein; Psort location: Cytoplasmic, score: 8.87.
  
 0.918
EEZ61279.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
   
 0.878
groL
Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.868
EEZ61396.1
Drug resistance MFS transporter, drug:H+ antiporter-2 family; KEGG: sgl:SG1466 1.3e-06 dethiobiotin synthase K01935; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the major facilitator superfamily.
   
 0.816
Your Current Organism:
Slackia exigua
NCBI taxonomy Id: 649764
Other names: S. exigua ATCC 700122, Slackia exigua ATCC 700122, Slackia exigua str. ATCC 700122, Slackia exigua strain ATCC 700122
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