STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
murEUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. (505 aa)    
Predicted Functional Partners:
murF
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
 
 0.999
murD
UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
 
 
 0.995
murG
Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
 
 0.957
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
 
 0.927
mraY
phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
 
 
 0.921
EEZ61153.1
KEGG: spn:SP_1978 5.8e-136 diaminopimelate decarboxylase K01586; Psort location: Cytoplasmic, score: 8.87.
     
 0.889
EEZ61908.1
Penicillin-binding protein, transpeptidase domain protein; KEGG: ace:Acel_1004 3.4e-76 peptidoglycan glycosyltransferase K05364; Psort location: CytoplasmicMembrane, score: 9.82.
  
 0.875
EEZ60469.1
CobB/CobQ-like protein; KEGG: lsl:LSL_0587 4.0e-34 cobyric acid synthase K01957; Psort location: Cytoplasmic, score: 8.87.
  
 0.845
EEZ60470.1
Mur ligase middle domain protein; KEGG: sab:SAB1824c 2.1e-60 probable UDP-N-acetylmuramyl tripeptide synthase K01924; Psort location: Cytoplasmic, score: 8.87.
  
 0.845
EEZ61182.1
Penicillin-binding protein, transpeptidase domain protein; KEGG: tfu:Tfu_3064 4.1e-71 peptidoglycan glycosyltransferase K05364; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family.
 
  
 0.818
Your Current Organism:
Slackia exigua
NCBI taxonomy Id: 649764
Other names: S. exigua ATCC 700122, Slackia exigua ATCC 700122, Slackia exigua str. ATCC 700122, Slackia exigua strain ATCC 700122
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.