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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaNDNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (364 aa)    
Predicted Functional Partners:
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
 0.998
holA
KEGG: gme:Gmet_2298 1.3e-26 DNA polymerase III, delta subunit K02340.
    
 0.990
dnaX
KEGG: art:Arth_0555 7.4e-88 DNA polymerase III, subunits gamma and tau K00961; Psort location: Cytoplasmic, score: 8.87.
   
 0.988
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
 
 
 0.988
EEZ61510.1
KEGG: mta:Moth_1872 8.3e-231 DNA polymerase III, alpha subunit K02337; Psort location: Cytoplasmic, score: 9.98.
    
 0.986
EEZ62144.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ecc:c2001 0.00025 rstB; sensor protein rstB K07639.
   
 0.982
EEZ62263.1
KEGG: gsu:GSU2230 6.2e-36 holB; DNA polymerase III, delta prime subunit K02341; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.980
xth
Exodeoxyribonuclease III; KEGG: lmf:LMOf2365_1807 3.0e-84 exoA; exodeoxyribonuclease K01142; Psort location: Cytoplasmic, score: 9.98.
   
 0.969
recF
DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.
 
  
 0.963
EEZ61279.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.957
Your Current Organism:
Slackia exigua
NCBI taxonomy Id: 649764
Other names: S. exigua ATCC 700122, Slackia exigua ATCC 700122, Slackia exigua str. ATCC 700122, Slackia exigua strain ATCC 700122
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