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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
folEGTP cyclohydrolase I; KEGG: cno:NT01CX_0377 2.1e-60 folE; GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 8.87. (188 aa)    
Predicted Functional Partners:
folP
Dihydropteroate synthase; KEGG: rso:RSc1527 1.6e-60 folP, RS03777; probable 7,8-dihydropteroate synthase protein K00796; Psort location: Cytoplasmic, score: 8.87.
 
 0.991
folB
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
 
 0.973
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
   
 0.898
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
    
  0.888
EEZ61172.1
HD domain protein; Psort location: Cytoplasmic, score: 8.87.
 
  
  0.836
rdgB
Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
 
 0.696
EEZ61547.1
Hypothetical protein; KEGG: ctc:CTC02272 1.3e-21 purine nucleoside phosphorylase K00755; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.685
EEZ61044.1
MazG family protein; KEGG: pha:PSHAa0740 4.8e-45 mazG; nucleoside triphosphate pyrophosphohydrolase, non-specific K02428; Psort location: Cytoplasmic, score: 8.87.
     
 0.653
hflB
ATP-dependent metallopeptidase HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
  
  
 0.650
folC
Bifunctional protein FolC; KEGG: tte:TTE0783 7.2e-74 folC; Folylpolyglutamate synthase K01930; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.613
Your Current Organism:
Slackia exigua
NCBI taxonomy Id: 649764
Other names: S. exigua ATCC 700122, Slackia exigua ATCC 700122, Slackia exigua str. ATCC 700122, Slackia exigua strain ATCC 700122
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