close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEZ60994.1DNA/RNA non-specific endonuclease; KEGG: spa:M6_Spy1739 2.9e-38 streptodornase K01150. (448 aa)    
Predicted Functional Partners:
EEZ60995.1
Hypothetical protein; Psort location: Extracellular, score: 8.82.
       0.574
EEZ60993.1
KEGG: chy:CHY_1912 2.3e-93 hom; homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 8.87.
       0.570
EEZ60996.1
Flavodoxin; KEGG: bcz:BCZK1264 1.9e-11 fldA; flavodoxin K00536; Psort location: Cytoplasmic, score: 8.87.
 
     0.498
rpoD
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
   0.448
EEZ62026.1
6-O-methylguanine DNA methyltransferase, DNA binding domain protein; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
  
  
 0.413
EEZ62187.1
DNA internalization competence protein ComEC/Rec2-like protein; Psort location: CytoplasmicMembrane, score: 9.97.
     
 0.406
EEZ60763.1
Putative membrane protein; KEGG: hdu:HD1844 0.00013 wecA; undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase K02851; Psort location: CytoplasmicMembrane, score: 9.99.
 
     0.404
Your Current Organism:
Slackia exigua
NCBI taxonomy Id: 649764
Other names: S. exigua ATCC 700122, Slackia exigua ATCC 700122, Slackia exigua str. ATCC 700122, Slackia exigua strain ATCC 700122
Server load: low (24%) [HD]