| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEZ60512.1 | EEZ61003.1 | HMPREF0762_01991 | HMPREF0762_01379 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.87. | Putative pyridoxal kinase; KEGG: blo:BL0934 2.1e-83 possible pyridoxine kinase K00868. | 0.490 |
| EEZ61003.1 | EEZ60512.1 | HMPREF0762_01379 | HMPREF0762_01991 | Putative pyridoxal kinase; KEGG: blo:BL0934 2.1e-83 possible pyridoxine kinase K00868. | Hypothetical protein; Psort location: Cytoplasmic, score: 8.87. | 0.490 |
| EEZ61003.1 | EEZ61004.1 | HMPREF0762_01379 | HMPREF0762_01380 | Putative pyridoxal kinase; KEGG: blo:BL0934 2.1e-83 possible pyridoxine kinase K00868. | GroES-like protein; KEGG: tte:TTE0695 3.5e-129 tdh; Threonine dehydrogenase and related Zn-dependent dehydrogenases K00100; Psort location: Cytoplasmic, score: 9.65. | 0.420 |
| EEZ61003.1 | EEZ61469.1 | HMPREF0762_01379 | HMPREF0762_00807 | Putative pyridoxal kinase; KEGG: blo:BL0934 2.1e-83 possible pyridoxine kinase K00868. | Pyridoxamine 5'-phosphate oxidase family protein; Psort location: Cytoplasmic, score: 8.87. | 0.706 |
| EEZ61003.1 | EEZ61897.1 | HMPREF0762_01379 | HMPREF0762_00534 | Putative pyridoxal kinase; KEGG: blo:BL0934 2.1e-83 possible pyridoxine kinase K00868. | Pyridoxal phosphate enzyme, YggS family; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.540 |
| EEZ61003.1 | nnrD | HMPREF0762_01379 | HMPREF0762_01293 | Putative pyridoxal kinase; KEGG: blo:BL0934 2.1e-83 possible pyridoxine kinase K00868. | YjeF domain protein; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. | 0.569 |
| EEZ61003.1 | pdxS | HMPREF0762_01379 | HMPREF0762_01523 | Putative pyridoxal kinase; KEGG: blo:BL0934 2.1e-83 possible pyridoxine kinase K00868. | Pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.891 |
| EEZ61003.1 | pdxT | HMPREF0762_01379 | HMPREF0762_01524 | Putative pyridoxal kinase; KEGG: blo:BL0934 2.1e-83 possible pyridoxine kinase K00868. | Pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.892 |
| EEZ61003.1 | thiD | HMPREF0762_01379 | HMPREF0762_00526 | Putative pyridoxal kinase; KEGG: blo:BL0934 2.1e-83 possible pyridoxine kinase K00868. | KEGG: cac:CAC3095 4.9e-68 thiK; phosphomethylpyrimidine kinase K00877:K00941; Psort location: Cytoplasmic, score: 8.87. | 0.653 |
| EEZ61004.1 | EEZ61003.1 | HMPREF0762_01380 | HMPREF0762_01379 | GroES-like protein; KEGG: tte:TTE0695 3.5e-129 tdh; Threonine dehydrogenase and related Zn-dependent dehydrogenases K00100; Psort location: Cytoplasmic, score: 9.65. | Putative pyridoxal kinase; KEGG: blo:BL0934 2.1e-83 possible pyridoxine kinase K00868. | 0.420 |
| EEZ61469.1 | EEZ61003.1 | HMPREF0762_00807 | HMPREF0762_01379 | Pyridoxamine 5'-phosphate oxidase family protein; Psort location: Cytoplasmic, score: 8.87. | Putative pyridoxal kinase; KEGG: blo:BL0934 2.1e-83 possible pyridoxine kinase K00868. | 0.706 |
| EEZ61897.1 | EEZ61003.1 | HMPREF0762_00534 | HMPREF0762_01379 | Pyridoxal phosphate enzyme, YggS family; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Putative pyridoxal kinase; KEGG: blo:BL0934 2.1e-83 possible pyridoxine kinase K00868. | 0.540 |
| nnrD | EEZ61003.1 | HMPREF0762_01293 | HMPREF0762_01379 | YjeF domain protein; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. | Putative pyridoxal kinase; KEGG: blo:BL0934 2.1e-83 possible pyridoxine kinase K00868. | 0.569 |
| nnrD | pdxS | HMPREF0762_01293 | HMPREF0762_01523 | YjeF domain protein; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. | Pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.503 |
| nnrD | pdxT | HMPREF0762_01293 | HMPREF0762_01524 | YjeF domain protein; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. | Pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.543 |
| pdxS | EEZ61003.1 | HMPREF0762_01523 | HMPREF0762_01379 | Pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | Putative pyridoxal kinase; KEGG: blo:BL0934 2.1e-83 possible pyridoxine kinase K00868. | 0.891 |
| pdxS | nnrD | HMPREF0762_01523 | HMPREF0762_01293 | Pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | YjeF domain protein; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. | 0.503 |
| pdxS | pdxT | HMPREF0762_01523 | HMPREF0762_01524 | Pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | Pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.999 |
| pdxS | thiD | HMPREF0762_01523 | HMPREF0762_00526 | Pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | KEGG: cac:CAC3095 4.9e-68 thiK; phosphomethylpyrimidine kinase K00877:K00941; Psort location: Cytoplasmic, score: 8.87. | 0.682 |
| pdxT | EEZ61003.1 | HMPREF0762_01524 | HMPREF0762_01379 | Pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | Putative pyridoxal kinase; KEGG: blo:BL0934 2.1e-83 possible pyridoxine kinase K00868. | 0.892 |