STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sppASignal peptide peptidase SppA, 36K type; KEGG: mac:MA4047 1.4e-36 proteinase IV K04773. (406 aa)    
Predicted Functional Partners:
EEZ60331.1
tRNA ligases class I (M); KEGG: bfs:BF4297 1.4e-37 metG; putative methionyl-tRNA synthetase K01874; Psort location: Cytoplasmic, score: 9.98; Belongs to the class-I aminoacyl-tRNA synthetase family.
       0.612
EEZ60333.1
Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; KEGG: cpr:CPR_1841 3.3e-110 phosphomannomutase K01840; Psort location: Cytoplasmic, score: 8.87.
       0.603
EEZ61086.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.99.
  
    0.496
EEZ61087.1
Hypothetical protein.
  
    0.474
EEZ61785.1
AMP-binding enzyme; KEGG: rpb:RPB_0580 6.6e-15 AMP-dependent synthetase and ligase K01897; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.468
topA
DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...]
     
 0.429
secD
Export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
  
   
 0.426
Your Current Organism:
Slackia exigua
NCBI taxonomy Id: 649764
Other names: S. exigua ATCC 700122, Slackia exigua ATCC 700122, Slackia exigua str. ATCC 700122, Slackia exigua strain ATCC 700122
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.