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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
recQKEGG: blo:BL1153 2.9e-148 recQ; ATP-dependent DNA helicase RecQ K03654; Psort location: Cytoplasmic, score: 8.87. (625 aa)    
Predicted Functional Partners:
topA
DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...]
 
 0.979
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.937
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
   
 0.891
EEZ62277.1
KEGG: bcl:ABC1086 1.1e-162 pcrA; ATP-dependent DNA helicase, UvrD/REP family K03657; Psort location: Cytoplasmic, score: 8.87.
 
 0.891
EEZ61368.1
SNF2 family N-terminal domain protein; KEGG: lwe:lwe1660 8.8e-117 DNA/RNA helicase protein K01529; Psort location: Cytoplasmic, score: 8.87.
 
 
 
 0.779
EEZ60388.1
DEAD/DEAH box helicase; KEGG: cff:CFF8240_0791 3.3e-94 putative ATP-dependent RNA helicase RhlE K01529; Psort location: Cytoplasmic, score: 8.87; Belongs to the DEAD box helicase family.
 
0.742
EEZ62144.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ecc:c2001 0.00025 rstB; sensor protein rstB K07639.
   
 0.722
recJ
KEGG: tte:TTE1191 5.3e-94 recJ; Single-stranded DNA-specific exonuclease K07462; Psort location: Cytoplasmic, score: 8.87.
    
0.663
EEZ61121.1
Putative DnaQ family exonuclease/DinG family helicase; KEGG: sth:STH1713 5.3e-94 ATP-dependent DNA helicase K03722; Psort location: Cytoplasmic, score: 8.87.
   
 0.621
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 0.620
Your Current Organism:
Slackia exigua
NCBI taxonomy Id: 649764
Other names: S. exigua ATCC 700122, Slackia exigua ATCC 700122, Slackia exigua str. ATCC 700122, Slackia exigua strain ATCC 700122
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