| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEZ61097.1 | glmM | HMPREF0762_01165 | HMPREF0762_01965 | KEGG: cpr:CPR_2431 1.2e-27 nagB; glucosamine-6-phosphate isomerase K02564; Psort location: Cytoplasmic, score: 8.87. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.914 |
| EEZ61097.1 | glmS | HMPREF0762_01165 | HMPREF0762_01291 | KEGG: cpr:CPR_2431 1.2e-27 nagB; glucosamine-6-phosphate isomerase K02564; Psort location: Cytoplasmic, score: 8.87. | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.916 |
| EEZ61097.1 | prs | HMPREF0762_01165 | HMPREF0762_01963 | KEGG: cpr:CPR_2431 1.2e-27 nagB; glucosamine-6-phosphate isomerase K02564; Psort location: Cytoplasmic, score: 8.87. | Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.536 |
| EEZ61785.1 | dapA | HMPREF0762_00419 | HMPREF0762_01229 | AMP-binding enzyme; KEGG: rpb:RPB_0580 6.6e-15 AMP-dependent synthetase and ligase K01897; Psort location: Cytoplasmic, score: 8.87. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.539 |
| EEZ61785.1 | glmM | HMPREF0762_00419 | HMPREF0762_01965 | AMP-binding enzyme; KEGG: rpb:RPB_0580 6.6e-15 AMP-dependent synthetase and ligase K01897; Psort location: Cytoplasmic, score: 8.87. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.497 |
| EEZ61785.1 | prs | HMPREF0762_00419 | HMPREF0762_01963 | AMP-binding enzyme; KEGG: rpb:RPB_0580 6.6e-15 AMP-dependent synthetase and ligase K01897; Psort location: Cytoplasmic, score: 8.87. | Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.514 |
| EEZ61887.1 | glmM | HMPREF0762_00521 | HMPREF0762_01965 | tRNA nucleotidyltransferase/poly(A) polymerase family protein; KEGG: ctc:CTC01205 1.3e-74 tRNA nucleotidyltransferase (CCA-adding enzyme) K00974; Psort location: Cytoplasmic, score: 8.87; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.671 |
| EEZ62157.1 | glmM | HMPREF0762_00249 | HMPREF0762_01965 | Hypothetical protein; Displays ATPase and GTPase activities. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.536 |
| EEZ62157.1 | glmU | HMPREF0762_00249 | HMPREF0762_01964 | Hypothetical protein; Displays ATPase and GTPase activities. | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.511 |
| dapA | EEZ61785.1 | HMPREF0762_01229 | HMPREF0762_00419 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | AMP-binding enzyme; KEGG: rpb:RPB_0580 6.6e-15 AMP-dependent synthetase and ligase K01897; Psort location: Cytoplasmic, score: 8.87. | 0.539 |
| dapA | glmM | HMPREF0762_01229 | HMPREF0762_01965 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.522 |
| dapA | glmS | HMPREF0762_01229 | HMPREF0762_01291 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.405 |
| glmM | EEZ61097.1 | HMPREF0762_01965 | HMPREF0762_01165 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | KEGG: cpr:CPR_2431 1.2e-27 nagB; glucosamine-6-phosphate isomerase K02564; Psort location: Cytoplasmic, score: 8.87. | 0.914 |
| glmM | EEZ61785.1 | HMPREF0762_01965 | HMPREF0762_00419 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | AMP-binding enzyme; KEGG: rpb:RPB_0580 6.6e-15 AMP-dependent synthetase and ligase K01897; Psort location: Cytoplasmic, score: 8.87. | 0.497 |
| glmM | EEZ61887.1 | HMPREF0762_01965 | HMPREF0762_00521 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | tRNA nucleotidyltransferase/poly(A) polymerase family protein; KEGG: ctc:CTC01205 1.3e-74 tRNA nucleotidyltransferase (CCA-adding enzyme) K00974; Psort location: Cytoplasmic, score: 8.87; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | 0.671 |
| glmM | EEZ62157.1 | HMPREF0762_01965 | HMPREF0762_00249 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Hypothetical protein; Displays ATPase and GTPase activities. | 0.536 |
| glmM | dapA | HMPREF0762_01965 | HMPREF0762_01229 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.522 |
| glmM | glmS | HMPREF0762_01965 | HMPREF0762_01291 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.974 |
| glmM | glmU | HMPREF0762_01965 | HMPREF0762_01964 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.993 |
| glmM | luxS | HMPREF0762_01965 | HMPREF0762_01966 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | S-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.461 |