STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEZ60557.1Methionine synthase, vitamin-B12 independent; KEGG: lsl:LSL_0129 2.3e-93 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase K00549; Psort location: Cytoplasmic, score: 8.87. (375 aa)    
Predicted Functional Partners:
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 0.968
luxS
S-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
    
 0.913
EEZ61358.1
Hypothetical protein; KEGG: pca:Pcar_2722 2.6e-19 5-methyltetrahydrofolate-homocysteine methyltransferase, truncation K00548; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.906
EEZ61380.1
O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; KEGG: bfr:BF3545 2.7e-161 O-acetylhomoserine (thiol)-lyase K01740; Psort location: Cytoplasmic, score: 9.98.
  
 
 0.905
EEZ60291.1
O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; KEGG: bth:BT2387 8.6e-158 O-acetylhomoserine (thiol)-lyase K01740; Psort location: Cytoplasmic, score: 9.98.
  
 
 0.903
EEZ60993.1
KEGG: chy:CHY_1912 2.3e-93 hom; homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 8.87.
   
 
 0.862
cysK
Cysteine synthase A; KEGG: bfr:BF4576 2.4e-107 cysteine synthase A K01738; Psort location: Cytoplasmic, score: 8.87; Belongs to the cysteine synthase/cystathionine beta- synthase family.
     
 0.841
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
   
 
 0.837
metG
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family.
     
 0.792
EEZ60331.1
tRNA ligases class I (M); KEGG: bfs:BF4297 1.4e-37 metG; putative methionyl-tRNA synthetase K01874; Psort location: Cytoplasmic, score: 9.98; Belongs to the class-I aminoacyl-tRNA synthetase family.
     
 0.792
Your Current Organism:
Slackia exigua
NCBI taxonomy Id: 649764
Other names: S. exigua ATCC 700122, Slackia exigua ATCC 700122, Slackia exigua str. ATCC 700122, Slackia exigua strain ATCC 700122
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.