node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
L083_1909 | L083_4513 | L083_1909 | L083_4513 | DNA polymerase III, subunit epsilon. | DNA-(apurinic or apyrimidinic site) lyase. | 0.700 |
L083_1909 | L083_7173 | L083_1909 | L083_7173 | DNA polymerase III, subunit epsilon. | DNA glycosylase/ap lyase, h2th DNA-binding protein; Belongs to the FPG family. | 0.508 |
L083_1909 | L083_8103 | L083_1909 | L083_8103 | DNA polymerase III, subunit epsilon. | DNA-(apurinic or apyrimidinic site) lyase; Belongs to the FPG family. | 0.508 |
L083_1909 | fpg | L083_1909 | L083_6903 | DNA polymerase III, subunit epsilon. | Formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.508 |
L083_1909 | lhr | L083_1909 | L083_6771 | DNA polymerase III, subunit epsilon. | DEAD/DEAH box helicase domain-containing protein. | 0.583 |
L083_1909 | nei1 | L083_1909 | L083_6774 | DNA polymerase III, subunit epsilon. | DNA-(apurinic or apyrimidinic site) lyase; Belongs to the FPG family. | 0.700 |
L083_1909 | nth | L083_1909 | L083_7901 | DNA polymerase III, subunit epsilon. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.708 |
L083_1909 | polA | L083_1909 | L083_2116 | DNA polymerase III, subunit epsilon. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.939 |
L083_1909 | recA | L083_1909 | L083_6759 | DNA polymerase III, subunit epsilon. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.616 |
L083_4513 | L083_1909 | L083_4513 | L083_1909 | DNA-(apurinic or apyrimidinic site) lyase. | DNA polymerase III, subunit epsilon. | 0.700 |
L083_4513 | L083_7173 | L083_4513 | L083_7173 | DNA-(apurinic or apyrimidinic site) lyase. | DNA glycosylase/ap lyase, h2th DNA-binding protein; Belongs to the FPG family. | 0.928 |
L083_4513 | L083_8103 | L083_4513 | L083_8103 | DNA-(apurinic or apyrimidinic site) lyase. | DNA-(apurinic or apyrimidinic site) lyase; Belongs to the FPG family. | 0.806 |
L083_4513 | fpg | L083_4513 | L083_6903 | DNA-(apurinic or apyrimidinic site) lyase. | Formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.776 |
L083_4513 | lhr | L083_4513 | L083_6771 | DNA-(apurinic or apyrimidinic site) lyase. | DEAD/DEAH box helicase domain-containing protein. | 0.851 |
L083_4513 | lysK | L083_4513 | L083_4511 | DNA-(apurinic or apyrimidinic site) lyase. | lysyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.773 |
L083_4513 | nei1 | L083_4513 | L083_6774 | DNA-(apurinic or apyrimidinic site) lyase. | DNA-(apurinic or apyrimidinic site) lyase; Belongs to the FPG family. | 0.914 |
L083_4513 | nth | L083_4513 | L083_7901 | DNA-(apurinic or apyrimidinic site) lyase. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.622 |
L083_4513 | polA | L083_4513 | L083_2116 | DNA-(apurinic or apyrimidinic site) lyase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.870 |
L083_4513 | recA | L083_4513 | L083_6759 | DNA-(apurinic or apyrimidinic site) lyase. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.572 |
L083_7173 | L083_1909 | L083_7173 | L083_1909 | DNA glycosylase/ap lyase, h2th DNA-binding protein; Belongs to the FPG family. | DNA polymerase III, subunit epsilon. | 0.508 |