node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AIU29627.1 | mhpC | Cul210931_0261 | Cul210931_0259 | Hypothetical protein. | Alpha/beta hydrolase family. | 0.587 |
AIU29627.1 | serB1 | Cul210931_0261 | Cul210931_0262 | Hypothetical protein. | Phosphoserine phosphatase. | 0.481 |
AIU30985.1 | metH | Cul210931_1654 | Cul210931_1113 | Phosphoglycerate dehydrogenase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.476 |
AIU30985.1 | serB1 | Cul210931_1654 | Cul210931_0262 | Phosphoglycerate dehydrogenase. | Phosphoserine phosphatase. | 0.710 |
AIU30985.1 | serC | Cul210931_1654 | Cul210931_0651 | Phosphoglycerate dehydrogenase. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.867 |
cpaE | serB1 | Cul210931_0264 | Cul210931_0262 | Pilus assembly protein. | Phosphoserine phosphatase. | 0.496 |
hisF | hisH | Cul210931_1428 | Cul210931_1431 | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.999 |
hisF | serB1 | Cul210931_1428 | Cul210931_0262 | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | Phosphoserine phosphatase. | 0.501 |
hisF | trpC | Cul210931_1428 | Cul210931_2269 | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | Bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Belongs to the TrpF family. | 0.723 |
hisH | hisF | Cul210931_1431 | Cul210931_1428 | Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.999 |
hisH | serB1 | Cul210931_1431 | Cul210931_0262 | Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | Phosphoserine phosphatase. | 0.473 |
hisH | trpC | Cul210931_1431 | Cul210931_2269 | Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | Bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Belongs to the TrpF family. | 0.631 |
metH | AIU30985.1 | Cul210931_1113 | Cul210931_1654 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Phosphoglycerate dehydrogenase. | 0.476 |
metH | serA | Cul210931_1113 | Cul210931_0948 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.476 |
metH | serB1 | Cul210931_1113 | Cul210931_0262 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Phosphoserine phosphatase. | 0.671 |
mhpC | AIU29627.1 | Cul210931_0259 | Cul210931_0261 | Alpha/beta hydrolase family. | Hypothetical protein. | 0.587 |
mhpC | serB1 | Cul210931_0259 | Cul210931_0262 | Alpha/beta hydrolase family. | Phosphoserine phosphatase. | 0.478 |
serA | metH | Cul210931_0948 | Cul210931_1113 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.476 |
serA | serB1 | Cul210931_0948 | Cul210931_0262 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Phosphoserine phosphatase. | 0.508 |
serA | serC | Cul210931_0948 | Cul210931_0651 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.989 |