STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gapGlyceraldehyde-3-phosphate dehydrogenase A; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (476 aa)    
Predicted Functional Partners:
pgk
Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
 
 0.997
zwf
Glucose-6-phosphate 1-dehydrogenase (G6PD); Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
  
 0.995
tpiA
Triosephosphate isomerase (TIM); Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 0.995
fbaA
Fructose-bisphosphate aldolase class 2; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
 0.981
pgl
6-phosphogluconolactonase.
   
 
 0.965
glpX
Fructose-1,6-bisphosphatase.
    
 0.960
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.952
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 0.938
pckG
Phosphoenolpyruvate carboxykinase GTP (PEP carboxykinase) (PEPCK); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
 
 
  
 0.932
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
   
 
 0.922
Your Current Organism:
Corynebacterium ulcerans
NCBI taxonomy Id: 65058
Other names: ATCC 51799, C. ulcerans, CCUG 2708, CIP 106504, DSM 46325, IMET 11148, JCM 10387, NCTC 7910, PCM 554, PCM:554
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