STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
nadENAD+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (543 aa)    
Predicted Functional Partners:
SEK25918.1
Bifunctional NMN adenylyltransferase/nudix hydrolase.
 
  
 0.980
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.980
nadK
NAD+ kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
    
 0.960
cobB
NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily.
    
 0.956
SEL92652.1
NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
     
 0.949
SEL92611.1
NAD(P) transhydrogenase subunit alpha; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family.
     
 0.930
SEK21394.1
NAD+ diphosphatase.
  
 
 0.927
SEL33882.1
Glutamate synthase (NADPH/NADH) large chain.
    
 0.871
SEK32698.1
Chorismate mutase.
  
 
 0.821
SEL88848.1
Sarcosine oxidase subunit alpha; Belongs to the GcvT family.
   
 
 0.812
Your Current Organism:
Halomonas daqiaonensis
NCBI taxonomy Id: 650850
Other names: CGMCC 1.9150, H. daqiaonensis, Halomonas daqiaonensis Qu et al. 2011, Halomonas sp. YCSA28, Halomonas sp. YCSA39, MCCC 1B00920, NCCB 100305, strain YCSA28
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