node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFR44934.1 | SFR65360.1 | SAMN05216203_0415 | SAMN05216203_2209 | ATP-dependent DNA helicase RecQ. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.950 |
SFR44934.1 | SFR76982.1 | SAMN05216203_0415 | SAMN05216203_2915 | ATP-dependent DNA helicase RecQ. | DNA repair exonuclease SbcCD nuclease subunit. | 0.994 |
SFR44934.1 | mutL | SAMN05216203_0415 | SAMN05216203_1134 | ATP-dependent DNA helicase RecQ. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.981 |
SFR44934.1 | mutS | SAMN05216203_0415 | SAMN05216203_2880 | ATP-dependent DNA helicase RecQ. | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.964 |
SFR44934.1 | polA | SAMN05216203_0415 | SAMN05216203_3347 | ATP-dependent DNA helicase RecQ. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.997 |
SFR44934.1 | rapA | SAMN05216203_0415 | SAMN05216203_3175 | ATP-dependent DNA helicase RecQ. | ATP-dependent helicase HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | 0.978 |
SFR44934.1 | recA | SAMN05216203_0415 | SAMN05216203_2882 | ATP-dependent DNA helicase RecQ. | Recombination protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.993 |
SFR48930.1 | SFR48941.1 | SAMN05216203_0826 | SAMN05216203_0827 | DNA ligase D. | DNA ligase D, 3'-phosphoesterase domain-containing protein. | 0.995 |
SFR48930.1 | SFR54501.1 | SAMN05216203_0826 | SAMN05216203_1287 | DNA ligase D. | DNA repair protein RadD. | 0.764 |
SFR48930.1 | SFR65360.1 | SAMN05216203_0826 | SAMN05216203_2209 | DNA ligase D. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.994 |
SFR48930.1 | SFR76982.1 | SAMN05216203_0826 | SAMN05216203_2915 | DNA ligase D. | DNA repair exonuclease SbcCD nuclease subunit. | 0.790 |
SFR48930.1 | polA | SAMN05216203_0826 | SAMN05216203_3347 | DNA ligase D. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.989 |
SFR48930.1 | rapA | SAMN05216203_0826 | SAMN05216203_3175 | DNA ligase D. | ATP-dependent helicase HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | 0.794 |
SFR48941.1 | SFR48930.1 | SAMN05216203_0827 | SAMN05216203_0826 | DNA ligase D, 3'-phosphoesterase domain-containing protein. | DNA ligase D. | 0.995 |
SFR48941.1 | SFR54501.1 | SAMN05216203_0827 | SAMN05216203_1287 | DNA ligase D, 3'-phosphoesterase domain-containing protein. | DNA repair protein RadD. | 0.764 |
SFR48941.1 | SFR65360.1 | SAMN05216203_0827 | SAMN05216203_2209 | DNA ligase D, 3'-phosphoesterase domain-containing protein. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.994 |
SFR48941.1 | SFR76982.1 | SAMN05216203_0827 | SAMN05216203_2915 | DNA ligase D, 3'-phosphoesterase domain-containing protein. | DNA repair exonuclease SbcCD nuclease subunit. | 0.790 |
SFR48941.1 | polA | SAMN05216203_0827 | SAMN05216203_3347 | DNA ligase D, 3'-phosphoesterase domain-containing protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.989 |
SFR48941.1 | rapA | SAMN05216203_0827 | SAMN05216203_3175 | DNA ligase D, 3'-phosphoesterase domain-containing protein. | ATP-dependent helicase HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | 0.794 |
SFR54501.1 | SFR48930.1 | SAMN05216203_1287 | SAMN05216203_0826 | DNA repair protein RadD. | DNA ligase D. | 0.764 |