STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ42484.1PFAM: Protein kinase domain; Tetratricopeptide repeat; COGs: COG0515 Serine/threonine protein kinase; InterProIPR019734:IPR000719:IPR013026:IPR017441:IPR 017442:IPR001440:IPR020635:IPR002290; KEGG: npu:Npun_R6348 TPR repeat-containing serine/threonin protein kinase; PFAM: Serine/threonine-protein kinase-like domain; Tetratricopeptide TPR_1 repeat-containing protein; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; Tetratricopeptide repeat; SPTR: Serine/threonine protein kinase with TPR repeats. (576 aa)    
Predicted Functional Partners:
AFZ45569.1
PFAM: WD domain, G-beta repeat; FHA domain; COGs: COG2319 FOG: WD40 repeat; InterProIPR000253:IPR019782:IPR017986:IPR019781:IPR 020472:IPR019775:IPR001680; KEGG: cyt:cce_2058 hypothetical protein; PFAM: Forkhead-associated protein; WD40 repeat, subgroup; SMART: Forkhead-associated protein; WD-40 repeat-containing protein; SPTR: Putative uncharacterized protein.
 0.895
AFZ44365.1
PFAM: Protein phosphatase 2C; COGs: COG0631 Serine/threonine protein phosphatase; InterPro IPR014045:IPR001932; KEGG: cyc:PCC7424_3475 protein serine/threonine phosphatase; PFAM: Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; SPTR: Protein phosphatase 2C.
 
 0.753
AFZ45938.1
PFAM: Protein phosphatase 2C; COGs: COG0631 Serine/threonine protein phosphatase; InterPro IPR014045:IPR001932; KEGG: cyh:Cyan8802_0156 protein serine/threonine phosphatase; PFAM: Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; SPTR: Protein serine/threonine phosphatase.
 
 0.744
AFZ42401.1
PFAM: Adenylate and Guanylate cyclase catalytic domain; FHA domain; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR000253:IPR001054:IPR003018; KEGG: ava:Ava_4645 adenylate/guanylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; Forkhead-associated protein; GAF domain protein; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; Forkhead-associated protein; GAF domain protein; SPTR: Adenylate and Guanylate cyclase catalytic domain protein.
 
 
 0.732
AFZ43721.1
PFAM: Protein phosphatase 2C; COGs: COG0631 Serine/threonine protein phosphatase; InterPro IPR001932:IPR014045; KEGG: npu:Npun_R0694 putative protein serine/threonine phosphatase; PFAM: Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; SPTR: Protein serine/threonine phosphatase.
 
 0.668
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 0.667
AFZ45417.1
PFAM: Stf0 sulphotransferase; Tetratricopeptide repeat; COGs: COG5010 Flp pilus assembly protein TadD contains TPR repeats; InterPro IPR019734:IPR013026:IPR001440; KEGG: ter:Tery_2707 glycosyl transferase family protein; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; SPTR: TPR repeat protein.
 
   0.665
AFZ45080.1
PFAM: CBS domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Hpt domain; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR017871:IPR000644:IPR003018:IPR 003661:IPR003594:IPR001789:IPR008207:IPR000014:IPR005467:I PR000700; KEGG: npu:Npun_F2363 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; CBS domain containing protein; GAF domain protein; response regulator receiv [...]
  
 
 0.625
AFZ44510.1
Multi-sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; GAF domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467:IPR001789:IPR000014:IPR000700:IPR 013655:IPR003018:IPR003661:IPR003594:IPR004358:IPR001610; KEGG: npu:Npun_F5679 multi-sensor hybrid multi-kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold-3 domain protein [...]
 
 
 
 0.624
AFZ45463.1
Tetratricopeptide TPR_1 repeat-containing protein; PFAM: Tetratricopeptide repeat; InterPro IPR019734:IPR013026:IPR001440; KEGG: ptm:GSPATT00038644001 hypothetical protein; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; SMART: Tetratricopeptide repeat; SPTR: TPR domain protein.
 
   0.597
Your Current Organism:
Halothece sp. PCC7418
NCBI taxonomy Id: 65093
Other names: Aphanothece halophytica 7418, Cyanothece sp. PCC 7418, H. sp. PCC 7418, Halothece sp. PCC 7418, Synechococcus sp. ATCC 29534 (no longer available), Synechococcus sp. PCC 7418
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