STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ42910.1CRISPR-associated protein, Cas6 family; PFAM: Uncharacterized conserved protein (DUF2276); TIGRFAM: CRISPR-associated endoribonuclease Cas6; COGs: COG5551 conserved hypothetical protein; InterPro IPR010156; KEGG: cyh:Cyan8802_4561 CRISPR-associated protein Cas6; SPTR: CRISPR-associated protein Cas6; TIGRFAM: CRISPR-associated protein Cas6. (271 aa)    
Predicted Functional Partners:
AFZ42911.1
CRISPR-associated exonuclease, Cas4 family; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.
 
   
 0.884
cas1
CRISPR-associated protein, Cas1 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
  
 0.866
cas2
CRISPR-associated protein, Cas2 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
   
 0.810
AFZ42922.1
KEGG: cyh:Cyan8802_4567 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.799
AFZ42914.1
TIGRFAM: CRISPR type I-D/CYANO-associated protein Csc1; InterPro IPR017576; KEGG: ava:Ava_4172 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: CRISPR-associated protein Csc1.
 
     0.793
AFZ42915.1
TIGRFAM: CRISPR type I-D/CYANO-associated protein Csc2; InterPro IPR017574; KEGG: mar:MAE_30710 hypothetical protein; SPTR: Similar to tr|A0YW94|A0YW94_9CYAN Hypothetical protein; TIGRFAM: CRISPR-associated protein Csc2.
 
     0.791
AFZ42921.1
PFAM: DEAD/DEAH box helicase; TIGRFAM: CRISPR-associated helicase Cas3, subtype CYANO; COGs: COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster; InterPro IPR017575:IPR011545:IPR014021:IPR014001; KEGG: ava:Ava_4165 DEAD/DEAH box helicase-like; PFAM: DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicase; SPTR: DEAD/DEAH box helicase-like; TIGRFAM: CRISPR-associated helicase, Cyano-type.
 
     0.746
AFZ42916.1
TIGRFAM: CRISPR type I-D/CYANO-associated protein Csc3/Cas10d; InterPro IPR017589; KEGG: ava:Ava_4170 hypothetical protein; SPTR: Similar to tr|A0YW95|A0YW95_9CYAN Hypothetical protein; TIGRFAM: CRISPR-associated protein Csc3.
 
     0.740
AFZ45059.1
KEGG: cyn:Cyan7425_0890 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.704
AFZ43985.1
PFAM: WD40-like Beta Propeller Repeat; COGs: COG0823 Periplasmic component of the Tol biopolymer transport system; InterPro IPR011659; KEGG: cyh:Cyan8802_2651 periplasmic component of the Tol biopolymer transport system-like protein; PFAM: WD40-like beta Propeller containing protein; SPTR: Periplasmic component of the Tol biopolymer transport system-like protein.
  
     0.583
Your Current Organism:
Halothece sp. PCC7418
NCBI taxonomy Id: 65093
Other names: Aphanothece halophytica 7418, Cyanothece sp. PCC 7418, H. sp. PCC 7418, Halothece sp. PCC 7418, Synechococcus sp. ATCC 29534 (no longer available), Synechococcus sp. PCC 7418
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