STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
AFZ43215.1CheA signal transduction histidine kinase; PFAM: CheW-like domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; Signal transducing histidine kinase, homodimeric domain; Hpt domain; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR005467:IPR001789:IPR002545:IPR008207:IPR 003594:IPR004358:IPR004105; KEGG: cyp:PCC8801_0764 CheA signal transduction histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; Hpt domain protein; Signal transducing histidine kinase homodimeric; C [...] (931 aa)    
Predicted Functional Partners:
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 0.999
AFZ44564.1
MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor; PFAM: CheB methylesterase; CheR methyltransferase, SAM binding domain; CheR methyltransferase, all-alpha domain; COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; InterPro IPR000673:IPR000780:IPR000014:IPR002052; KEGG: alv:Alvin_1169 MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor; PFAM: MCP methyltransferase CheR-type; CheB methylesterase; SMART: MCP methyltransferase CheR-type; SPTR: MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor; TIGRFAM: PAS sensor protein.
 
 0.999
AFZ43213.1
PFAM: CheW-like domain; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: cyp:PCC8801_0767 CheW protein; PFAM: CheW domain protein; SMART: CheW domain protein; SPTR: CheW protein.
 
 0.994
AFZ44969.1
Methyl-accepting chemotaxis sensory transducer with GAF sensor; PFAM: HAMP domain; GAF domain; Methyl-accepting chemotaxis protein (MCP) signaling domain; COGs: COG0840 Methyl-accepting chemotaxis protein; InterProIPR003660:IPR003018:IPR004089:IPR008611:IPR 016132; KEGG: cyh:Cyan8802_2778 methyl-accepting chemotaxis sensory transducer with GAF sensor; PFAM: chemotaxis sensory transducer; GAF domain protein; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; GAF domain protein; histidine kinase HAMP region domain protein; SPTR: Methyl-accepting chemotaxis [...]
 
 
 0.992
AFZ42465.1
PFAM: HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain; COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089:IPR013026:IPR003660; KEGG: npu:Npun_F5963 methyl-accepting chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SPTR: Methyl-accepting chemotaxis sensory transducer.
 
 
 0.986
AFZ43212.1
PFAM: Methyl-accepting chemotaxis protein (MCP) signaling domain; CHASE3 domain; COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089; KEGG: cyh:Cyan8802_0788 methyl-accepting chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; SPTR: Methyl-accepting chemotaxis sensory transducer.
 
 
 0.986
AFZ45080.1
PFAM: CBS domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Hpt domain; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR017871:IPR000644:IPR003018:IPR 003661:IPR003594:IPR001789:IPR008207:IPR000014:IPR005467:I PR000700; KEGG: npu:Npun_F2363 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; CBS domain containing protein; GAF domain protein; response regulator receiv [...]
 
 
 0.985
AFZ43253.1
PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; GAF domain; His Kinase A (phosphoacceptor) domain; PAS fold; Hpt domain; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR005467:IPR001789:IPR000700:IPR 008207:IPR003018:IPR003661:IPR003594:IPR004358:IPR003660:I PR013656; KEGG: ana:all2875 two-component hybrid sensor and regulator; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; histidine kinase HAMP region domain [...]
 
 
0.983
AFZ42845.1
Methyl-accepting chemotaxis sensory transducer with GAF sensor; PFAM: HAMP domain; GAF domain; Methyl-accepting chemotaxis protein (MCP) signaling domain; COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR016132:IPR004089:IPR003660:IPR003018; KEGG: cyc:PCC7424_2782 methyl-accepting chemotaxis sensory transducer with GAF sensor; PFAM: chemotaxis sensory transducer; GAF domain protein; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; GAF domain protein; histidine kinase HAMP region domain protein; SPTR: Methyl-accepting chemotaxis protein si [...]
 
 
 0.982
AFZ44863.1
PFAM: HAMP domain; Cache domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Hpt domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467:IPR001789:IPR000014:IPR000700:IPR 003660:IPR008207:IPR001610:IPR003661:IPR003594:IPR004010:I PR013656:IPR013655:IPR004358; KEGG: hch:HCH_00809 signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; histidine kinase [...]
 
 
0.982
Your Current Organism:
Halothece sp. PCC7418
NCBI taxonomy Id: 65093
Other names: Aphanothece halophytica 7418, Cyanothece sp. PCC 7418, H. sp. PCC 7418, Halothece sp. PCC 7418, Synechococcus sp. ATCC 29534 (no longer available), Synechococcus sp. PCC 7418
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