STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ43619.1PFAM: Type III restriction enzyme, res subunit; COGs: COG4096 Type I site-specific restriction-modification system R (restriction) subunit and related helicase; InterPro IPR007409:IPR006935; KEGG: nwi:Nwi_0270 DEAD/DEAH box helicase; PFAM: type III restriction protein res subunit; protein of unknown function DUF450; PRIAM: Type I site-specific deoxyribonuclease; SPTR: EcoEI R domain protein. (642 aa)    
Predicted Functional Partners:
AFZ43373.1
Site-specific DNA-methyltransferase (adenine-specific); PFAM: N-6 DNA Methylase; HsdM N-terminal domain; COGs: COG0286 Type I restriction-modification system methyltransferase subunit; InterPro IPR002052:IPR002296:IPR003356; KEGG: dol:Dole_2095 N-6 DNA methylase; PFAM: N-6 DNA methylase; PRIAM: Site-specific DNA-methyltransferase (adenine-specific); SPTR: N-6 DNA methylase.
 
 
 0.907
AFZ43377.1
PFAM: Type I restriction modification DNA specificity domain; COGs: COG0732 Restriction endonuclease S subunits; InterPro IPR000055; KEGG: vsp:VS_1379 type I restriction enzyme EcoKI S subunit; PFAM: restriction modification system DNA specificity domain; SPTR: Type I restriction modification DNA specificity domain protein.
 
 
 0.858
AFZ43618.1
Site-specific DNA-methyltransferase (adenine-specific); PFAM: N-6 DNA Methylase; HsdM N-terminal domain; COGs: COG0286 Type I restriction-modification system methyltransferase subunit; InterPro IPR003356:IPR002296; KEGG: ttu:TERTU_3913 putative TypeI restriction-modification system, methylase subunit; PFAM: N-6 DNA methylase; PRIAM: Site-specific DNA-methyltransferase (adenine-specific); SPTR: Type I restriction-modification system DNA methylase.
 
 
 0.855
AFZ45137.1
PFAM: N-6 DNA Methylase; HsdM N-terminal domain; TIGRFAM: type I restriction system adenine methylase (hsdM); COGs: COG0286 Type I restriction-modification system methyltransferase subunit; InterPro IPR002296:IPR002052:IPR004546:IPR003356; KEGG: ana:all2688 type I restriction enzyme, modification chain; PFAM: N-6 DNA methylase; SPTR: Type I RM system M subunit; TIGRFAM: type I restriction-modification system, M subunit.
 
 
 0.765
AFZ45526.1
Site-specific DNA-methyltransferase (adenine-specific); PFAM: N-6 DNA Methylase; HsdM N-terminal domain; COGs: COG0286 Type I restriction-modification system methyltransferase subunit; InterPro IPR002296:IPR003356; KEGG: ttu:TERTU_3913 putative TypeI restriction-modification system, methylase subunit; PFAM: N-6 DNA methylase; PRIAM: Site-specific DNA-methyltransferase (adenine-specific); SPTR: Type I restriction-modification system DNA methylase.
 
 
 0.742
AFZ43616.1
PFAM: Type I restriction modification DNA specificity domain; COGs: COG0732 Restriction endonuclease S subunits; InterPro IPR000055; KEGG: cch:Cag_1122 restriction endonuclease S subunits-like; PFAM: restriction modification system DNA specificity domain; SPTR: Putative uncharacterized protein.
 
 
 0.709
AFZ45918.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR016132:IPR005467:IPR001789:IPR000014:IPR 000700:IPR003018:IPR013655:IPR013656:IPR013767:IPR003661:I PR003594:IPR004358:IPR001610; KEGG: ava:Ava_4701 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; GAF domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidin [...]
   
 
 0.645
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.623
AFZ45528.1
PFAM: Type I restriction modification DNA specificity domain; COGs: COG0732 Restriction endonuclease S subunits; InterPro IPR000055; KEGG: tjr:TherJR_0900 restriction modification system DNA specificity domain protein; PFAM: restriction modification system DNA specificity domain; SPTR: Restriction modification system DNA specificity domain protein.
 
 
 0.613
AFZ45142.1
PFAM: Type I restriction modification DNA specificity domain; COGs: COG0732 Restriction endonuclease S subunits; InterPro IPR000055; KEGG: tgr:Tgr7_1778 type I restriction-modification system specificity subunit; PFAM: restriction modification system DNA specificity domain; SPTR: Type I restriction-modification system specificity subunit.
 
 
 0.606
Your Current Organism:
Halothece sp. PCC7418
NCBI taxonomy Id: 65093
Other names: Aphanothece halophytica 7418, Cyanothece sp. PCC 7418, H. sp. PCC 7418, Halothece sp. PCC 7418, Synechococcus sp. ATCC 29534 (no longer available), Synechococcus sp. PCC 7418
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