STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ureFUrease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. (222 aa)    
Predicted Functional Partners:
ureE
UreE urease accessory domain-containing protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
  
 0.998
ureD
Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.998
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
 
 0.994
ureC
PFAM: Urease alpha-subunit, N-terminal domain; Amidohydrolase family; TIGRFAM: urease, alpha subunit; COGs: COG0804 Urea amidohydrolase (urease) alpha subunit; InterProIPR017951:IPR017950:IPR005848:IPR011612:IPR 006680:IPR017952; KEGG: npu:Npun_F0825 urease subunit alpha; PFAM: amidohydrolase; Urease alpha-subunit domain-containing protein; PRIAM: Urease; SPTR: Urease subunit alpha; TIGRFAM: urease, alpha subunit.
 
 
 0.993
ureB
PFAM: Urease beta subunit; TIGRFAM: urease, beta subunit; COGs: COG0832 Urea amidohydrolase (urease) beta subunit; InterPro IPR002019; KEGG: npu:Npun_F0824 urease subunit beta; PFAM: Urease beta subunit; PRIAM: Urease; SPTR: Urease subunit beta; TIGRFAM: urease, beta subunit; Belongs to the urease beta subunit family.
 
 
 0.974
ureA
PFAM: Urease, gamma subunit; TIGRFAM: urease, gamma subunit; COGs: COG0831 Urea amidohydrolase (urease) gamma subunit; InterPro IPR002026:IPR012010; KEGG: mar:MAE_45220 urease gamma subunit; PFAM: Urease gamma subunit region; PRIAM: Urease; SPTR: Urease subunit gamma; TIGRFAM: urease, gamma subunit; Belongs to the urease gamma subunit family.
 
 
 0.969
AFZ43475.1
Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR012202:IPR003495:IPR004392; KEGG: syp:SYNPCC7002_A0203 hydrogenase isoenzymes formation protein; HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB.
  
 
 0.916
AFZ44102.1
Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR004392:IPR012202:IPR003495; KEGG: syn:sll1079 hydrogenase expression/formation protein; HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB.
  
 
 0.916
AFZ43699.1
KEGG: cyc:PCC7424_4085 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.532
AFZ43659.1
ABC transporter, periplasmic solute-binding protein, putative; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence; urea ABC transporter, urea binding protein; COGs: COG0683 ABC-type branched-chain amino acid transport systems periplasmic component; InterPro IPR017909:IPR006311; KEGG: amr:AM1_5992 ABC transporter, periplasmic solute-binding protein, putative; SPTR: ABC transporter, periplasmic solute-binding protein, putative.
 
   
 0.489
Your Current Organism:
Halothece sp. PCC7418
NCBI taxonomy Id: 65093
Other names: Aphanothece halophytica 7418, Cyanothece sp. PCC 7418, H. sp. PCC 7418, Halothece sp. PCC 7418, Synechococcus sp. ATCC 29534 (no longer available), Synechococcus sp. PCC 7418
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