STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ43880.1Coproporphyrinogen III oxidase, anaerobic; PFAM: Radical SAM superfamily; HemN C-terminal region; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; COGs: COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductase; InterPro IPR006638:IPR007197:IPR010723:IPR004558; KEGG: ava:Ava_4393 coproporphyrinogen III oxidase; PFAM: HemN domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Coproporphyrinogen III oxidase, anaerobic; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; Belongs to the anaerobic coproporphyrinogen-III oxida [...] (463 aa)    
Predicted Functional Partners:
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 
 0.948
hemF
Coproporphyrinogen oxidase; Involved in the heme and chlorophyll biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
    
 0.937
AFZ43049.1
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
    
 0.923
AFZ43879.1
PFAM: Heme oxygenase; COGs: COG5398 Heme oxygenase; InterPro IPR018207:IPR002051:IPR016053; KEGG: cyc:PCC7424_2604 heme oxygenase; PFAM: Haem oxygenase-like; PRIAM: Heme oxygenase; SPTR: Heme oxygenase.
 
   
 0.621
AFZ42794.1
Pyruvate ferredoxin/flavodoxin oxidoreductase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin.
     
 0.515
acsF
Mg-protoporphyrin IX monomethyl ester (oxidative) cyclase; Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME); Belongs to the AcsF family.
     
 0.480
AFZ43013.1
PFAM: Pyridine nucleotide-disulphide oxidoreductase; COGs: COG1252 NADH dehydrogenase FAD-containing subunit; InterPro IPR013027; KEGG: cyt:cce_3407 sulfide-quinone reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Sulfide quinone reductase.
  
    0.463
AFZ44863.1
PFAM: HAMP domain; Cache domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Hpt domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467:IPR001789:IPR000014:IPR000700:IPR 003660:IPR008207:IPR001610:IPR003661:IPR003594:IPR004010:I PR013656:IPR013655:IPR004358; KEGG: hch:HCH_00809 signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; histidine kinase [...]
  
  
 0.405
AFZ44828.1
Protein of unknown function DUF344; PFAM: Polyphosphate kinase 2 (PPK2); TIGRFAM: polyphosphate:AMP phosphotransferase; COGs: COG2326 conserved hypothetical protein; InterPro IPR005660; KEGG: mar:MAE_62470 hypothetical protein; PFAM: protein of unknown function DUF344; SPTR: Putative uncharacterized protein.
  
    0.401
Your Current Organism:
Halothece sp. PCC7418
NCBI taxonomy Id: 65093
Other names: Aphanothece halophytica 7418, Cyanothece sp. PCC 7418, H. sp. PCC 7418, Halothece sp. PCC 7418, Synechococcus sp. ATCC 29534 (no longer available), Synechococcus sp. PCC 7418
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