STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ44391.1PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; COGs: COG0033 Phosphoglucomutase; InterProIPR005844:IPR005845:IPR005846:IPR005843:IPR 005841:IPR016066; KEGG: ter:Tery_1084 phosphoglucomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/be [...] (543 aa)    
Predicted Functional Partners:
AFZ44999.1
Glycogen/starch/alpha-glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
 
 
 0.986
pgi
PFAM: Phosphoglucose isomerase; COGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR001672:IPR018189:IPR000169; KEGG: ana:alr1050 glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI); SPTR: Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 0.986
AFZ44610.1
PFAM: Carbohydrate phosphorylase; Protein of unknown function (DUF3417); TIGRFAM: alpha-glucan phosphorylases; COGs: COG0058 Glucan phosphorylase; InterPro IPR000811:IPR011834; KEGG: ava:Ava_2996 alpha-glucan phosphorylase; PFAM: glycosyl transferase family 35; PRIAM: Phosphorylase; SPTR: Phosphorylase; TIGRFAM: alpha-glucan phosphorylase.
  
 
 0.980
AFZ42754.1
PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; TIGRFAM: transketolase, bacterial and yeast; COGs: COG0021 Transketolase; InterProIPR005474:IPR020826:IPR005478:IPR005475:IPR 005476; KEGG: cyc:PCC7424_4065 transketolase; PFAM: Transketolase domain-containing protein; Transketolase central region; SPTR: Transketolase; TIGRFAM: transketolase; Belongs to the transketolase family.
  
 
 0.941
glgC
Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
    
 0.934
AFZ42687.1
PFAM: 4-alpha-glucanotransferase; TIGRFAM: 4-alpha-glucanotransferase; COGs: COG1640 4-alpha-glucanotransferase; InterPro IPR003385; KEGG: ana:alr3871 4-alpha-glucanotransferase; PFAM: glycoside hydrolase family 77; PRIAM: 4-alpha-glucanotransferase; SPTR: 4-alpha-glucanotransferase; TIGRFAM: 4-alpha-glucanotransferase.
  
 
 0.929
rpiA
Ribose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
  
 
 0.929
AFZ45346.1
Alpha-1,6-glucosidase, pullulanase-type; PFAM: Domain of unknown function (DUF3372); Carbohydrate-binding module 48 (Isoamylase N-terminal domain); Alpha amylase, catalytic domain; TIGRFAM: alpha-1,6-glucosidases, pullulanase-type; COGs: COG1523 Type II secretory pathway pullulanase PulA and related glycosidase; InterPro IPR011839:IPR004193:IPR006047; KEGG: chl:Chy400_0954 alpha-1,6-glucosidase, pullulanase-type; PFAM: glycoside hydrolase family 13 domain protein; alpha amylase catalytic region; SPTR: Alpha-1,6-glucosidase, pullulanase-type; TIGRFAM: alpha-1,6-glucosidase, pullulanase- [...]
    
 0.923
glk
PFAM: Glucokinase; TIGRFAM: glucokinase, proteobacterial type; COGs: COG0837 Glucokinase; InterPro IPR003836; KEGG: ava:Ava_0933 glucokinase; PFAM: Glucokinase; PRIAM: Glucokinase; SPTR: Glucokinase; TIGRFAM: glucokinase; Belongs to the bacterial glucokinase family.
     
 0.922
AFZ43137.1
PFAM: ROK family; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: cyt:cce_2522 ROK family protein; PFAM: ROK family protein; SPTR: ROK family protein.
    
 0.920
Your Current Organism:
Halothece sp. PCC7418
NCBI taxonomy Id: 65093
Other names: Aphanothece halophytica 7418, Cyanothece sp. PCC 7418, H. sp. PCC 7418, Halothece sp. PCC 7418, Synechococcus sp. ATCC 29534 (no longer available), Synechococcus sp. PCC 7418
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