STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ45516.1PFAM: 5-formyltetrahydrofolate cyclo-ligase family; TIGRFAM: 5,10-methenyltetrahydrofolate synthetase; COGs: COG0212 5-formyltetrahydrofolate cyclo-ligase; InterPro IPR002698; KEGG: cyc:PCC7424_4701 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase; SPTR: 5-formyltetrahydrofolate cyclo-ligase; TIGRFAM: 5-formyltetrahydrofolate cyclo-ligase; manually curated. (169 aa)    
Predicted Functional Partners:
folD
5,10-methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
    
 0.934
purN
Formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
    
 0.917
pheT
phenylalanyl-tRNA synthetase beta subunit; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterProIPR004532:IPR002547:IPR005121:IPR005146:IPR 005147; KEGG: cyc:PCC7424_4756 phenylalanyl-tRNA synthetase subunit beta; PFAM: B3/4 domain protein; t-RNA-binding domain-containing protein; tRNA synthetase B5; ferredoxin-fold anticodon-binding; PRIAM: Phenylalanine--tRNA ligase; SPTR: Pheny [...]
 
  
 0.569
AFZ42539.1
PFAM: Rhomboid family; COGs: COG0705 membrane protein; InterPro IPR002610; KEGG: cyc:PCC7424_0711 rhomboid family protein; PFAM: Rhomboid family protein; SPTR: Rhomboid family protein.
  
    0.435
AFZ44429.1
PFAM: Rhomboid family; COGs: COG0705 membrane protein; InterPro IPR002610; KEGG: naz:Aazo_4331 rhomboid family protein; PFAM: Rhomboid family protein; SPTR: Peptidase, S54 (Rhomboid) family.
  
    0.435
AFZ44789.1
PFAM: Rhomboid family; COGs: COG0705 membrane protein; InterPro IPR002610; KEGG: olu:OSTLU_26597 predicted protein; PFAM: Rhomboid family protein; SPTR: Predicted protein.
  
    0.435
AFZ44874.1
PFAM: Rhomboid family; InterPro IPR002610; KEGG: mar:MAE_02880 putative peptidase; PFAM: Rhomboid family protein; SPTR: Similar to tr|Q4C4J5|Q4C4J5_CROWT Rhomboid-like protein.
  
    0.435
AFZ45515.1
Delta-12 acyl-phospholipid desaturase; PFAM: Fatty acid desaturase; COGs: COG3239 Fatty acid desaturase; InterPro IPR005804; KEGG: amr:AM1_4659 fatty acid desaturase (delta(12) desaturase); PFAM: fatty acid desaturase; SPTR: Fatty acid desaturase (Delta(12) desaturase).
       0.418
Your Current Organism:
Halothece sp. PCC7418
NCBI taxonomy Id: 65093
Other names: Aphanothece halophytica 7418, Cyanothece sp. PCC 7418, H. sp. PCC 7418, Halothece sp. PCC 7418, Synechococcus sp. ATCC 29534 (no longer available), Synechococcus sp. PCC 7418
Server load: low (36%) [HD]