STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ45569.1PFAM: WD domain, G-beta repeat; FHA domain; COGs: COG2319 FOG: WD40 repeat; InterProIPR000253:IPR019782:IPR017986:IPR019781:IPR 020472:IPR019775:IPR001680; KEGG: cyt:cce_2058 hypothetical protein; PFAM: Forkhead-associated protein; WD40 repeat, subgroup; SMART: Forkhead-associated protein; WD-40 repeat-containing protein; SPTR: Putative uncharacterized protein. (900 aa)    
Predicted Functional Partners:
AFZ42989.1
Hypothetical protein; PFAM: Metallo-beta-lactamase superfamily; COGs: COG1236 exonuclease of the beta-lactamase fold involved in RNA processing; InterPro IPR001307; KEGG: ana:all3220 hypothetical protein; SPTR: All3220 protein.
  
 0.936
AFZ42484.1
PFAM: Protein kinase domain; Tetratricopeptide repeat; COGs: COG0515 Serine/threonine protein kinase; InterProIPR019734:IPR000719:IPR013026:IPR017441:IPR 017442:IPR001440:IPR020635:IPR002290; KEGG: npu:Npun_R6348 TPR repeat-containing serine/threonin protein kinase; PFAM: Serine/threonine-protein kinase-like domain; Tetratricopeptide TPR_1 repeat-containing protein; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; Tetratricopeptide repeat; SPTR: Serine/threonine protein kinase with TPR repeats.
 0.895
AFZ44418.1
PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; FHA domain; TIGRFAM: penicillin-binding protein, 1A family; COGs: COG0744 Membrane carboxypeptidase (penicillin-binding protein); InterPro IPR000253:IPR001264:IPR001460:IPR011816; KEGG: cyc:PCC7424_3011 FHA modulated glycosyl transferase/transpeptidase; PFAM: glycosyl transferase family 51; Forkhead-associated protein; penicillin-binding protein transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SMART: Forkhead-associated protein; SPTR: FHA modulated glycosyl transferase/transpeptidase; TIGRFAM: penicillin [...]
   
 
 0.828
AFZ43325.1
Catalytic domain-containing protein of components of various dehydrogenase complexes; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Biotin-requiring enzyme; TIGRFAM: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterProIPR003016:IPR000276:IPR000089:IPR004167:IPR 001078; KEGG: cyh:Cyan8802_1261 branched-chain alpha-keto acid dehydrogenase subunit E2; PFAM: catalytic domain-containing protein of components of v [...]
   
 
 0.802
AFZ43390.1
Penicillin-binding protein, 1A family; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein, 1A family; COGs: COG0744 Membrane carboxypeptidase (penicillin-binding protein); InterPro IPR011816:IPR001264:IPR001460; KEGG: cyt:cce_2453 penicillin-binding protein 1A; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Penicillin-binding protein, 1A family; TIGRFAM: penicillin-binding protein, 1A family.
   
 
 0.797
AFZ44777.1
PFAM: Mov34/MPN/PAD-1 family; COGs: COG1310 metal-dependent protease of the PAD1/JAB1 superfamily; InterPro IPR000555; KEGG: syp:SYNPCC7002_A1403 Mov34/MPN/PAD-1 family protein; PFAM: Mov34/MPN/PAD-1 family protein; SMART: Mov34/MPN/PAD-1 family protein; SPTR: Mov34/MPN/PAD-1 family protein.
   
  0.783
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
 0.768
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 0.746
AFZ43915.1
KEGG: gbm:Gbem_3785 hypothetical protein; SPTR: Putative uncharacterized protein.
   
 0.745
AFZ45080.1
PFAM: CBS domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Hpt domain; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR017871:IPR000644:IPR003018:IPR 003661:IPR003594:IPR001789:IPR008207:IPR000014:IPR005467:I PR000700; KEGG: npu:Npun_F2363 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; CBS domain containing protein; GAF domain protein; response regulator receiv [...]
 
 
 0.728
Your Current Organism:
Halothece sp. PCC7418
NCBI taxonomy Id: 65093
Other names: Aphanothece halophytica 7418, Cyanothece sp. PCC 7418, H. sp. PCC 7418, Halothece sp. PCC 7418, Synechococcus sp. ATCC 29534 (no longer available), Synechococcus sp. PCC 7418
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