| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCK79117.1 | pyrH | TOL2_C09500 | TOL2_C00110 | Conserved uncharacterized protein. | PyrH: uridylate kinase (Uridine monophosphate kinase). | 0.782 |
| frr | guaA | TOL2_C16380 | TOL2_C14360 | Frr: ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | GuaA: GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.680 |
| frr | murEF | TOL2_C16380 | TOL2_C12140 | Frr: ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | MurEF: fusion protein; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.554 |
| frr | pyrH | TOL2_C16380 | TOL2_C00110 | Frr: ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | PyrH: uridylate kinase (Uridine monophosphate kinase). | 0.878 |
| frr | rpsB | TOL2_C16380 | TOL2_C16350 | Frr: ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | RpsB: 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.996 |
| frr | rpsJ | TOL2_C16380 | TOL2_C34840 | Frr: ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | RpsJ: 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.965 |
| frr | tig | TOL2_C16380 | TOL2_C04360 | Frr: ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | Tig: trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.908 |
| frr | tsf | TOL2_C16380 | TOL2_C16360 | Frr: ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | Tsf: elongation factor Ts (EF-Ts); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.997 |
| frr | uppS | TOL2_C16380 | TOL2_C16390 | Frr: ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | UppS: undecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.963 |
| guaA | frr | TOL2_C14360 | TOL2_C16380 | GuaA: GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Frr: ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.680 |
| guaA | murEF | TOL2_C14360 | TOL2_C12140 | GuaA: GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | MurEF: fusion protein; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.509 |
| guaA | pyrH | TOL2_C14360 | TOL2_C00110 | GuaA: GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | PyrH: uridylate kinase (Uridine monophosphate kinase). | 0.737 |
| guaA | rpsB | TOL2_C14360 | TOL2_C16350 | GuaA: GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | RpsB: 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.759 |
| guaA | rpsJ | TOL2_C14360 | TOL2_C34840 | GuaA: GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | RpsJ: 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.752 |
| guaA | tig | TOL2_C14360 | TOL2_C04360 | GuaA: GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Tig: trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.717 |
| guaA | tsf | TOL2_C14360 | TOL2_C16360 | GuaA: GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Tsf: elongation factor Ts (EF-Ts); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.669 |
| guaA | uppS | TOL2_C14360 | TOL2_C16390 | GuaA: GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | UppS: undecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.530 |
| murEF | frr | TOL2_C12140 | TOL2_C16380 | MurEF: fusion protein; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | Frr: ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.554 |
| murEF | guaA | TOL2_C12140 | TOL2_C14360 | MurEF: fusion protein; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | GuaA: GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.509 |
| murEF | pyrH | TOL2_C12140 | TOL2_C00110 | MurEF: fusion protein; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | PyrH: uridylate kinase (Uridine monophosphate kinase). | 0.656 |