Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCK78421.1Putative mercuric reductase (Hg(II) reductase); Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (714 aa)    
Predicted Functional Partners:
CCK80963.1
Conserved uncharacterized protein, DUF1499; Signal peptide.
     0.844
CCK78420.1
FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
 
  
 0.842
CCK82138.1
Fusion protein: glycine cleavage T-protein and glycine hydroxymethyltransferase.
  
 0.796
msrAB
MsrAB: peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
  
 0.779
prs
Prs: ribose-phosphate pyrophosphokinase (RPPK); Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 0.767
CCK81384.1
Conserved uncharacterized protein; Signal peptide.
 
     0.738
CCK80014.1
Tetratricopeptide (TRP1+2) repeat protein; Signal peptide.
  
 
 0.725
guaB
GuaB: inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.716
pfaA
PfaA: polyketide-type polyunsaturated fatty acid synthase.
  
 
 0.702
atpA
AtpA: ATP synthase subunit alpha (F-ATPase subunit alpha) (ATP synthase F1 sector subunit alpha); Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.
  
 0.682
Your Current Organism:
Desulfobacula toluolica
NCBI taxonomy Id: 651182
Other names: D. toluolica Tol2, Desulfobacula toluolica DSM 7467, Desulfobacula toluolica Tol2, Desulfobacula toluolica str. Tol2, Desulfobacula toluolica strain Tol2
Server load: low (24%) [HD]