Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cysECysE: serine acetyltransferase. (328 aa)    
Predicted Functional Partners:
cysK
CysK: cysteine synthase (O-acetylserine sulfhydrylase).
 
 0.997
cysS2
CysS2: predicted cysteinyl-tRNA synthetase.
  
 0.987
CCK81824.1
Transferase hexapeptide repeat containing protein.
  
  
 
0.927
serB
SerB: phosphoserine phosphatase.
  
 
 0.879
cysS
CysS: cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
  
 0.875
hom
Hom: homoserine dehydrogenase.
  
  
 0.853
CCK80662.1
Phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein.
  
 
 0.829
glyA
GlyA: serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.824
CCK80822.1
CDP-alcohol phosphatidyltransferase; Signal peptide; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
    
  0.820
trpB2
TrpB2: tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
     
 0.811
Your Current Organism:
Desulfobacula toluolica
NCBI taxonomy Id: 651182
Other names: D. toluolica Tol2, Desulfobacula toluolica DSM 7467, Desulfobacula toluolica Tol2, Desulfobacula toluolica str. Tol2, Desulfobacula toluolica strain Tol2
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