Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hmgLHmgL: predicted hydroxymethylglutaryl-CoA lyase. (374 aa)    
Predicted Functional Partners:
acsA2
AcsA2: acetoacetyl-CoA synthetase.
 
 
 0.957
nifJ
NifJ: pyruvate-flavodoxin oxidoreductase.
  
 
 0.940
atoB
AtoB: acetyl-CoA acetyltransferase (acetoacetyl-CoA thiolase); Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.929
fadA
FadA: 3-ketoacyl-CoA thiolase (Beta-ketothiolase) (Acetyl-CoA acyltransferase); Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.928
CCK79306.1
Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.928
thlA
ThlA: acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.928
mvaB
MvaB: hydroxymehtylglutaryl-CoA lyase.
  
  
 
0.927
korB2
KorB2: 2-oxoglutarate synthase, subunit B.
 
 
 0.922
korA3
KorA3: 2-oxoglutarate synthase, alpha subunit.
  
 
 0.912
padG1
PadG1: phenylglyoxylate:acceptor oxidoreductase, subunit G.
   
 
 0.904
Your Current Organism:
Desulfobacula toluolica
NCBI taxonomy Id: 651182
Other names: D. toluolica Tol2, Desulfobacula toluolica DSM 7467, Desulfobacula toluolica Tol2, Desulfobacula toluolica str. Tol2, Desulfobacula toluolica strain Tol2
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