Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCK79050.1Extracellular solute-binding protein, family 1; Signal peptide. (373 aa)    
Predicted Functional Partners:
CCK79049.1
Uncharacterized protein related to methyltransferase type 11.
       0.773
CCK79028.1
Predicted ABC transport system ATP-binding protein.
  
 
 0.768
modC2
ModC2: molybdate ABC transporter, ATP-binding protein; Belongs to the ABC transporter superfamily.
  
 
 0.768
CCK79048.1
Choline/ethanolamine kinase.
       0.723
CCK79047.1
Uncharacterized protein related to glutamyl tRNA-reductase.
       0.625
CCK79046.1
Phosphoesterase family protein; Signal peptide.
       0.583
topA
TopA: DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DN [...]
     
 0.547
CCK81789.1
Predicted polyketide synthase.
 
  
 0.547
CCK82040.1
Transcriptional regulator, XRE family.
 
   
 0.450
CCK79051.1
VanZ family protein.
       0.412
Your Current Organism:
Desulfobacula toluolica
NCBI taxonomy Id: 651182
Other names: D. toluolica Tol2, Desulfobacula toluolica DSM 7467, Desulfobacula toluolica Tol2, Desulfobacula toluolica str. Tol2, Desulfobacula toluolica strain Tol2
Server load: low (24%) [HD]