node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCK78394.1 | CCK82138.1 | TOL2_C02240 | TOL2_C39830 | Putative thymidylate synthase. | Fusion protein: glycine cleavage T-protein and glycine hydroxymethyltransferase. | 0.968 |
CCK78394.1 | glyA | TOL2_C02240 | TOL2_C33730 | Putative thymidylate synthase. | GlyA: serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.927 |
CCK78394.1 | metF2 | TOL2_C02240 | TOL2_C09070 | Putative thymidylate synthase. | MetF2: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.908 |
CCK78599.1 | metF2 | TOL2_C04290 | TOL2_C09070 | Conserved uncharacterized protein. | MetF2: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.770 |
CCK79074.1 | metF2 | TOL2_C09060 | TOL2_C09070 | Conserved uncharacterized protein. | MetF2: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.871 |
CCK80730.1 | metF2 | TOL2_C25710 | TOL2_C09070 | Uncharacterized protein. | MetF2: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.764 |
CCK80999.1 | CCK82138.1 | TOL2_C28390 | TOL2_C39830 | Predicted dihydropteroate synthase. | Fusion protein: glycine cleavage T-protein and glycine hydroxymethyltransferase. | 0.938 |
CCK80999.1 | glyA | TOL2_C28390 | TOL2_C33730 | Predicted dihydropteroate synthase. | GlyA: serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.908 |
CCK80999.1 | metF2 | TOL2_C28390 | TOL2_C09070 | Predicted dihydropteroate synthase. | MetF2: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.959 |
CCK81392.1 | metF2 | TOL2_C32350 | TOL2_C09070 | Conserved uncharacterized protein. | MetF2: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.764 |
CCK81485.1 | metF2 | TOL2_C33280 | TOL2_C09070 | Conserved uncharacterized protein. | MetF2: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.772 |
CCK82138.1 | CCK78394.1 | TOL2_C39830 | TOL2_C02240 | Fusion protein: glycine cleavage T-protein and glycine hydroxymethyltransferase. | Putative thymidylate synthase. | 0.968 |
CCK82138.1 | CCK80999.1 | TOL2_C39830 | TOL2_C28390 | Fusion protein: glycine cleavage T-protein and glycine hydroxymethyltransferase. | Predicted dihydropteroate synthase. | 0.938 |
CCK82138.1 | glyA | TOL2_C39830 | TOL2_C33730 | Fusion protein: glycine cleavage T-protein and glycine hydroxymethyltransferase. | GlyA: serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.969 |
CCK82138.1 | metF2 | TOL2_C39830 | TOL2_C09070 | Fusion protein: glycine cleavage T-protein and glycine hydroxymethyltransferase. | MetF2: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.946 |
CCK82373.1 | metF2 | TOL2_C42170 | TOL2_C09070 | Conserved uncharacterized protein. | MetF2: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.774 |
glyA | CCK78394.1 | TOL2_C33730 | TOL2_C02240 | GlyA: serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Putative thymidylate synthase. | 0.927 |
glyA | CCK80999.1 | TOL2_C33730 | TOL2_C28390 | GlyA: serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Predicted dihydropteroate synthase. | 0.908 |
glyA | CCK82138.1 | TOL2_C33730 | TOL2_C39830 | GlyA: serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Fusion protein: glycine cleavage T-protein and glycine hydroxymethyltransferase. | 0.969 |
glyA | metF2 | TOL2_C33730 | TOL2_C09070 | GlyA: serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | MetF2: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.928 |