Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cyaA2Cya: adenylate cyclase. (1289 aa)    
Predicted Functional Partners:
CCK79153.1
Putative ppGpp synthesis/degradation protein, RelA domain.
  
  
  0.938
CCK80504.1
Putative adenylate cyclase family protein.
  
  
 0.923
relA
RelA: GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
    
 0.913
CCK78938.1
Adenylate cyclase with chase sensor domain.
     
 0.908
CCK81106.1
Adenylate cyclase with chase sensor domain.
     
 0.908
nrdD
NrdD: anaerobic ribonucleoside-triphosphate reductase.
    
 0.908
ndk
Ndk: nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
  
 
  0.903
CCK79932.1
Adenylate cyclase.
     
  0.900
CCK81676.1
Putative oxidoreductase.
  
 
  0.833
ribBA
RibBA: fusion protein: 3,4-dihydroxy-2-butanone 4-phosphate synthase and GTP cyclohydrolase-2; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
   
 
  0.802
Your Current Organism:
Desulfobacula toluolica
NCBI taxonomy Id: 651182
Other names: D. toluolica Tol2, Desulfobacula toluolica DSM 7467, Desulfobacula toluolica Tol2, Desulfobacula toluolica str. Tol2, Desulfobacula toluolica strain Tol2
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