| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| fchA | ftcD | TOL2_C11860 | TOL2_C11400 | FchA: methenyltetrahydrofolate cyclohydrolase. | FtcD: formimidoyltetrahydrofolate cyclodeaminase. | 0.942 |
| fchA | hutH2 | TOL2_C11860 | TOL2_C18480 | FchA: methenyltetrahydrofolate cyclohydrolase. | HutH2: histidine ammonia-lyase (histidase). | 0.525 |
| fchA | pal | TOL2_C11860 | TOL2_C18180 | FchA: methenyltetrahydrofolate cyclohydrolase. | Pal: predicted phenylalanine ammonia-lyase. | 0.518 |
| ftcD | fchA | TOL2_C11400 | TOL2_C11860 | FtcD: formimidoyltetrahydrofolate cyclodeaminase. | FchA: methenyltetrahydrofolate cyclohydrolase. | 0.942 |
| ftcD | hutH2 | TOL2_C11400 | TOL2_C18480 | FtcD: formimidoyltetrahydrofolate cyclodeaminase. | HutH2: histidine ammonia-lyase (histidase). | 0.792 |
| ftcD | hutI | TOL2_C11400 | TOL2_C18460 | FtcD: formimidoyltetrahydrofolate cyclodeaminase. | HutI: imidazolonepropionase (imidazolone-5-propionate hydrolase). | 0.948 |
| ftcD | pal | TOL2_C11400 | TOL2_C18180 | FtcD: formimidoyltetrahydrofolate cyclodeaminase. | Pal: predicted phenylalanine ammonia-lyase. | 0.777 |
| ftcD | speB | TOL2_C11400 | TOL2_C01070 | FtcD: formimidoyltetrahydrofolate cyclodeaminase. | SpeB: agmatinase (Agmatine ureohydrolase); Belongs to the arginase family. | 0.913 |
| gcvPB | hutH2 | TOL2_C20970 | TOL2_C18480 | GcvPB: glycine dehydrogenase (decarboxylating), glycine cleavage system P protein, subunit 2. | HutH2: histidine ammonia-lyase (histidase). | 0.444 |
| gcvPB | hutU | TOL2_C20970 | TOL2_C18470 | GcvPB: glycine dehydrogenase (decarboxylating), glycine cleavage system P protein, subunit 2. | HutU: urocanate hydratase (urocanase); Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. | 0.429 |
| gcvPB | pal | TOL2_C20970 | TOL2_C18180 | GcvPB: glycine dehydrogenase (decarboxylating), glycine cleavage system P protein, subunit 2. | Pal: predicted phenylalanine ammonia-lyase. | 0.444 |
| hisD | hisHF | TOL2_C39770 | TOL2_C40970 | HisD: histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | HisHF: imidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF; Belongs to the HisA/HisF family. | 0.999 |
| hisD | hutH2 | TOL2_C39770 | TOL2_C18480 | HisD: histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | HutH2: histidine ammonia-lyase (histidase). | 0.922 |
| hisD | pal | TOL2_C39770 | TOL2_C18180 | HisD: histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | Pal: predicted phenylalanine ammonia-lyase. | 0.922 |
| hisHF | hisD | TOL2_C40970 | TOL2_C39770 | HisHF: imidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF; Belongs to the HisA/HisF family. | HisD: histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.999 |
| hisHF | hutH2 | TOL2_C40970 | TOL2_C18480 | HisHF: imidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF; Belongs to the HisA/HisF family. | HutH2: histidine ammonia-lyase (histidase). | 0.522 |
| hisHF | pal | TOL2_C40970 | TOL2_C18180 | HisHF: imidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF; Belongs to the HisA/HisF family. | Pal: predicted phenylalanine ammonia-lyase. | 0.522 |
| hutH2 | fchA | TOL2_C18480 | TOL2_C11860 | HutH2: histidine ammonia-lyase (histidase). | FchA: methenyltetrahydrofolate cyclohydrolase. | 0.525 |
| hutH2 | ftcD | TOL2_C18480 | TOL2_C11400 | HutH2: histidine ammonia-lyase (histidase). | FtcD: formimidoyltetrahydrofolate cyclodeaminase. | 0.792 |
| hutH2 | gcvPB | TOL2_C18480 | TOL2_C20970 | HutH2: histidine ammonia-lyase (histidase). | GcvPB: glycine dehydrogenase (decarboxylating), glycine cleavage system P protein, subunit 2. | 0.444 |