Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hyfRHyfR: two component system response regulator of hydrogenase 4, sigma54-specific. (474 aa)    
Predicted Functional Partners:
CCK80105.1
Two component system sensor histidine kinase.
 
 
 0.939
rpoN
RpoN: RNA polymerase sigma54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
   
 0.635
CCK80104.1
Two component system response regulator.
 
    
0.598
CCK80099.1
Two component system sensor histidine kinase.
 
 
 0.529
CCK80103.1
Two component system sensor histidine kinase.
 
 
  
0.458
fliM
FliM: flagellar motor switch protein.
  
  
 0.439
fliP
FliP: flagellar biosynthesis protein, protein export component; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.
  
  
 0.423
Your Current Organism:
Desulfobacula toluolica
NCBI taxonomy Id: 651182
Other names: D. toluolica Tol2, Desulfobacula toluolica DSM 7467, Desulfobacula toluolica Tol2, Desulfobacula toluolica str. Tol2, Desulfobacula toluolica strain Tol2
Server load: low (26%) [HD]