| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aroC | pabB | TOL2_C19910 | TOL2_C33640 | AroC: chorismate synthase (5-enolpyruvylshikimate-3-phosphate phospholyase); Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | PabB: p-aminobenzoate synthase, subunit I. | 0.970 |
| aroC | pheA | TOL2_C19910 | TOL2_C19950 | AroC: chorismate synthase (5-enolpyruvylshikimate-3-phosphate phospholyase); Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | PheA: P-protein (includes: chorismate mutase and prephenate dehydratase). | 0.996 |
| aroC | trpA | TOL2_C19910 | TOL2_C41280 | AroC: chorismate synthase (5-enolpyruvylshikimate-3-phosphate phospholyase); Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | TrpA: tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.767 |
| aroC | trpB2 | TOL2_C19910 | TOL2_C41270 | AroC: chorismate synthase (5-enolpyruvylshikimate-3-phosphate phospholyase); Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | TrpB2: tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.644 |
| aroC | trpC | TOL2_C19910 | TOL2_C22530 | AroC: chorismate synthase (5-enolpyruvylshikimate-3-phosphate phospholyase); Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | TrpC: indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.629 |
| aroC | trpD | TOL2_C19910 | TOL2_C05370 | AroC: chorismate synthase (5-enolpyruvylshikimate-3-phosphate phospholyase); Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | TrpD: anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.527 |
| aroC | trpD2 | TOL2_C19910 | TOL2_C22520 | AroC: chorismate synthase (5-enolpyruvylshikimate-3-phosphate phospholyase); Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | TrpD2: antrhranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.527 |
| aroC | trpE | TOL2_C19910 | TOL2_C22500 | AroC: chorismate synthase (5-enolpyruvylshikimate-3-phosphate phospholyase); Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | TrpE: anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high c [...] | 0.971 |
| aroC | trpG | TOL2_C19910 | TOL2_C22510 | AroC: chorismate synthase (5-enolpyruvylshikimate-3-phosphate phospholyase); Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | TrpG: anthranileta synthase, component II 2.6.1.85. | 0.970 |
| pabB | aroC | TOL2_C33640 | TOL2_C19910 | PabB: p-aminobenzoate synthase, subunit I. | AroC: chorismate synthase (5-enolpyruvylshikimate-3-phosphate phospholyase); Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.970 |
| pabB | pheA | TOL2_C33640 | TOL2_C19950 | PabB: p-aminobenzoate synthase, subunit I. | PheA: P-protein (includes: chorismate mutase and prephenate dehydratase). | 0.925 |
| pabB | trpA | TOL2_C33640 | TOL2_C41280 | PabB: p-aminobenzoate synthase, subunit I. | TrpA: tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.976 |
| pabB | trpB2 | TOL2_C33640 | TOL2_C41270 | PabB: p-aminobenzoate synthase, subunit I. | TrpB2: tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.978 |
| pabB | trpC | TOL2_C33640 | TOL2_C22530 | PabB: p-aminobenzoate synthase, subunit I. | TrpC: indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.994 |
| pabB | trpD | TOL2_C33640 | TOL2_C05370 | PabB: p-aminobenzoate synthase, subunit I. | TrpD: anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.990 |
| pabB | trpD2 | TOL2_C33640 | TOL2_C22520 | PabB: p-aminobenzoate synthase, subunit I. | TrpD2: antrhranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.991 |
| pabB | trpE | TOL2_C33640 | TOL2_C22500 | PabB: p-aminobenzoate synthase, subunit I. | TrpE: anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high c [...] | 0.876 |
| pabB | trpF | TOL2_C33640 | TOL2_C22540 | PabB: p-aminobenzoate synthase, subunit I. | TrpF: N-(5?-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. | 0.960 |
| pabB | trpG | TOL2_C33640 | TOL2_C22510 | PabB: p-aminobenzoate synthase, subunit I. | TrpG: anthranileta synthase, component II 2.6.1.85. | 0.999 |
| pheA | aroC | TOL2_C19950 | TOL2_C19910 | PheA: P-protein (includes: chorismate mutase and prephenate dehydratase). | AroC: chorismate synthase (5-enolpyruvylshikimate-3-phosphate phospholyase); Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.996 |
