| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCK80628.1 | bioA | TOL2_C24670 | TOL2_C38190 | Radical SAM domain protein. | BioA: predicted adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 0.799 |
| CCK80628.1 | bioB | TOL2_C24670 | TOL2_C38290 | Radical SAM domain protein. | BioB: biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.900 |
| CCK80628.1 | bioD | TOL2_C24670 | TOL2_C38170 | Radical SAM domain protein. | BioD: dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.986 |
| CCK80628.1 | bioF | TOL2_C24670 | TOL2_C38180 | Radical SAM domain protein. | BioF: 8-amino-7-oxononanoate synthase. | 0.634 |
| CCK80628.1 | birA | TOL2_C24670 | TOL2_C02960 | Radical SAM domain protein. | BirA: predicted biotin--acteyl-CiA-carboxylase ligase. | 0.919 |
| CCK80628.1 | birA2 | TOL2_C24670 | TOL2_C12270 | Radical SAM domain protein. | BirA2: biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.956 |
| CCK80628.1 | kbl | TOL2_C24670 | TOL2_C06920 | Radical SAM domain protein. | Kbl: 2-amino-3-ketobutyrate CoA ligase (glycine C-acetyltransferase). | 0.634 |
| CCK80628.1 | murEF | TOL2_C24670 | TOL2_C12140 | Radical SAM domain protein. | MurEF: fusion protein; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.480 |
| CCK80628.1 | nadA | TOL2_C24670 | TOL2_C03450 | Radical SAM domain protein. | NadA: Quinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.491 |
| CCK80628.1 | pfaA | TOL2_C24670 | TOL2_C34430 | Radical SAM domain protein. | PfaA: polyketide-type polyunsaturated fatty acid synthase. | 0.528 |
| bioA | CCK80628.1 | TOL2_C38190 | TOL2_C24670 | BioA: predicted adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | Radical SAM domain protein. | 0.799 |
| bioA | bioB | TOL2_C38190 | TOL2_C38290 | BioA: predicted adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | BioB: biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.996 |
| bioA | bioD | TOL2_C38190 | TOL2_C38170 | BioA: predicted adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | BioD: dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.999 |
| bioA | bioF | TOL2_C38190 | TOL2_C38180 | BioA: predicted adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | BioF: 8-amino-7-oxononanoate synthase. | 0.999 |
| bioA | birA | TOL2_C38190 | TOL2_C02960 | BioA: predicted adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | BirA: predicted biotin--acteyl-CiA-carboxylase ligase. | 0.432 |
| bioA | birA2 | TOL2_C38190 | TOL2_C12270 | BioA: predicted adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | BirA2: biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.586 |
| bioA | kbl | TOL2_C38190 | TOL2_C06920 | BioA: predicted adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | Kbl: 2-amino-3-ketobutyrate CoA ligase (glycine C-acetyltransferase). | 0.805 |
| bioA | pfaA | TOL2_C38190 | TOL2_C34430 | BioA: predicted adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | PfaA: polyketide-type polyunsaturated fatty acid synthase. | 0.582 |
| bioB | CCK80628.1 | TOL2_C38290 | TOL2_C24670 | BioB: biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Radical SAM domain protein. | 0.900 |
| bioB | bioA | TOL2_C38290 | TOL2_C38190 | BioB: biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | BioA: predicted adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 0.996 |