Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
acnAAcnA: aconitate hydratase (aconitase); Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (883 aa)    
Predicted Functional Partners:
gltA
GltA: citrate synthase; Belongs to the citrate synthase family.
 
 0.998
gltA2
GltA2: citrate synthase, type II; Belongs to the citrate synthase family.
 
 0.997
icd
Icd: isocitrate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 0.995
fumC
FumC: fumarate hydratase class II (fumarase C); Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.958
fadB
FadB: 3-hydroxyacyl-CoA dehydrogenase, NAD-binding.
   
 0.914
prpF
PrpF: predicted 3-methylitaconate isomerase.
 
  
 0.909
mdh
Mdh: malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.899
atpA
AtpA: ATP synthase subunit alpha (F-ATPase subunit alpha) (ATP synthase F1 sector subunit alpha); Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.
   
 0.896
mdh2
Mdh2: malate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.868
sodB
SodB: superoxid dismutase, iron-type.
   
 
 0.856
Your Current Organism:
Desulfobacula toluolica
NCBI taxonomy Id: 651182
Other names: D. toluolica Tol2, Desulfobacula toluolica DSM 7467, Desulfobacula toluolica Tol2, Desulfobacula toluolica str. Tol2, Desulfobacula toluolica strain Tol2
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