Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CCK81307.1DnaJ domain heat shock protein; Signal peptide. (165 aa)    
Predicted Functional Partners:
dapB
DapB: dihydrodipicolinate reductase; Belongs to the DapB family.
  
  
 0.872
htpG
HtpG: chaperone protein; Molecular chaperone. Has ATPase activity.
  
 0.836
pfaA
PfaA: polyketide-type polyunsaturated fatty acid synthase.
  
 
 0.831
CCK81305.1
Predicted aminoglycoside phosphotransferase.
   
   0.772
CCK81308.1
Alpha/beta hydrolase fold protein.
   
 
 0.759
plsB
PlsB: glycerol-3-phosphate acyltransferase; Belongs to the GPAT/DAPAT family.
       0.747
grpE
GrpE: HSP70 cofactor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...]
  
 
 0.746
groL
GroL: 60kDa chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 0.734
bamH1
BamH1: NADH-quinone oxidoreductase, subunit F.
   
  0.709
bamH3
BamH3: NADH-quinone oxidoreductase, subunit F.
   
  0.709
Your Current Organism:
Desulfobacula toluolica
NCBI taxonomy Id: 651182
Other names: D. toluolica Tol2, Desulfobacula toluolica DSM 7467, Desulfobacula toluolica Tol2, Desulfobacula toluolica str. Tol2, Desulfobacula toluolica strain Tol2
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