Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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[Homology]
Score
CCK81313.1Putative exonuclease modulated with PAS domain; Signal peptide. (716 aa)    
Predicted Functional Partners:
dnaN
DnaN: DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...]
   
 0.942
holA
HolA: putative DNA-directed DNA polymerase III, delta subunit.
    
 0.938
dnaE
DnaE: DNA-directed DNA polymerase III, alpha subunit.
    
 0.932
holB
HolB: putative DNA-directed DNA polymerase III, delta subunit.
  
 0.925
dnaX
DnaX: DNA polymerase III, subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
 0.925
CCK81315.1
Predicted CBS domian and cyclic nucleotide-regulated nucleotidyltransferase.
 
   
 0.891
CCK81312.1
Na+/solute symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
     0.861
lemA
LemA family protein; Signal anchor.
       0.731
CCK80058.1
Two component system sensor histidine kinase.
  
 
 0.685
CCK79625.1
Two component system sensor histidine kinase, hybrid.
  
 
 0.683
Your Current Organism:
Desulfobacula toluolica
NCBI taxonomy Id: 651182
Other names: D. toluolica Tol2, Desulfobacula toluolica DSM 7467, Desulfobacula toluolica Tol2, Desulfobacula toluolica str. Tol2, Desulfobacula toluolica strain Tol2
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