| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCK81431.1 | ahcY | TOL2_C32740 | TOL2_C32720 | PfkB family carbohydrate kinase. | AhcY: adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.746 |
| CCK81431.1 | apt | TOL2_C32740 | TOL2_C17740 | PfkB family carbohydrate kinase. | Apt: adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.676 |
| CCK81431.1 | hisA | TOL2_C32740 | TOL2_C28280 | PfkB family carbohydrate kinase. | HisA: 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Belongs to the HisA/HisF family. | 0.806 |
| CCK81431.1 | metK | TOL2_C32740 | TOL2_C32730 | PfkB family carbohydrate kinase. | MetK: S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.687 |
| CCK81431.1 | pfk | TOL2_C32740 | TOL2_C22130 | PfkB family carbohydrate kinase. | Pfk: phosphofructokinase. | 0.670 |
| CCK81431.1 | purA | TOL2_C32740 | TOL2_C30230 | PfkB family carbohydrate kinase. | PurA: adenylosuccinate lyase, subunit A; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.794 |
| CCK81431.1 | rpe | TOL2_C32740 | TOL2_C14870 | PfkB family carbohydrate kinase. | Rpe: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | 0.597 |
| CCK81431.1 | rpoB | TOL2_C32740 | TOL2_C34880 | PfkB family carbohydrate kinase. | RpoB: DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.707 |
| CCK81431.1 | rpsK | TOL2_C32740 | TOL2_C34590 | PfkB family carbohydrate kinase. | RpsK: 30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. | 0.634 |
| CCK81431.1 | sodB | TOL2_C32740 | TOL2_C06590 | PfkB family carbohydrate kinase. | SodB: superoxid dismutase, iron-type. | 0.774 |
| ahcY | CCK81431.1 | TOL2_C32720 | TOL2_C32740 | AhcY: adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | PfkB family carbohydrate kinase. | 0.746 |
| ahcY | metK | TOL2_C32720 | TOL2_C32730 | AhcY: adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | MetK: S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.940 |
| ahcY | rpoB | TOL2_C32720 | TOL2_C34880 | AhcY: adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | RpoB: DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.472 |
| apt | CCK81431.1 | TOL2_C17740 | TOL2_C32740 | Apt: adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | PfkB family carbohydrate kinase. | 0.676 |
| apt | purA | TOL2_C17740 | TOL2_C30230 | Apt: adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | PurA: adenylosuccinate lyase, subunit A; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.860 |
| hisA | CCK81431.1 | TOL2_C28280 | TOL2_C32740 | HisA: 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Belongs to the HisA/HisF family. | PfkB family carbohydrate kinase. | 0.806 |
| metK | CCK81431.1 | TOL2_C32730 | TOL2_C32740 | MetK: S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | PfkB family carbohydrate kinase. | 0.687 |
| metK | ahcY | TOL2_C32730 | TOL2_C32720 | MetK: S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | AhcY: adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.940 |
| metK | purA | TOL2_C32730 | TOL2_C30230 | MetK: S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | PurA: adenylosuccinate lyase, subunit A; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.512 |
| metK | rpe | TOL2_C32730 | TOL2_C14870 | MetK: S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | Rpe: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | 0.627 |