Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCK81663.1Conserved uncharacterized protein; Signal peptide. (364 aa)    
Predicted Functional Partners:
radC2
RadC2: DNA repair protein radC homolog; Belongs to the UPF0758 family.
  
  
 0.763
gyrA
GyrA: DNA gyrase, subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
       0.757
CCK81660.1
Uncharacterized protein.
       0.756
pgk
Pgk: phosphoglyerate kinase; Belongs to the phosphoglycerate kinase family.
       0.728
CCK81658.1
Conserved uncharacterized protein.
       0.656
flgF
FlgF: flagellar basal-body rod protein.
    
   0.637
CCK80822.1
CDP-alcohol phosphatidyltransferase; Signal peptide; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
    0.426
CCK78775.1
Conserved uncharacterized protein; Signal peptide.
  
     0.421
thlA
ThlA: acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
     
 0.411
Your Current Organism:
Desulfobacula toluolica
NCBI taxonomy Id: 651182
Other names: D. toluolica Tol2, Desulfobacula toluolica DSM 7467, Desulfobacula toluolica Tol2, Desulfobacula toluolica str. Tol2, Desulfobacula toluolica strain Tol2
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.