| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| deaD | nnrD | TOL2_C36300 | TOL2_C10880 | DeaD: cold-shock DEAD box protein; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. | YjeF: uncharacterized predicted carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase [...] | 0.765 |
| deaD | pfaA | TOL2_C36300 | TOL2_C34430 | DeaD: cold-shock DEAD box protein; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. | PfaA: polyketide-type polyunsaturated fatty acid synthase. | 0.710 |
| deaD | pnp | TOL2_C36300 | TOL2_C04640 | DeaD: cold-shock DEAD box protein; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. | Pnp: polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase); Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.771 |
| deaD | rbgA | TOL2_C36300 | TOL2_C29080 | DeaD: cold-shock DEAD box protein; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. | RbgA: ribosome biogenesis GTPase; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | 0.755 |
| deaD | rplC | TOL2_C36300 | TOL2_C34830 | DeaD: cold-shock DEAD box protein; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. | RplC: 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.783 |
| deaD | rplD | TOL2_C36300 | TOL2_C34820 | DeaD: cold-shock DEAD box protein; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. | RplD: 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 0.738 |
| deaD | rplK | TOL2_C36300 | TOL2_C34920 | DeaD: cold-shock DEAD box protein; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. | RplK: 50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.709 |
| deaD | rplM | TOL2_C36300 | TOL2_C13610 | DeaD: cold-shock DEAD box protein; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. | RplM: 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.731 |
| deaD | rpmD | TOL2_C36300 | TOL2_C34650 | DeaD: cold-shock DEAD box protein; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. | RpmD: 50S ribosomal protein L30. | 0.702 |
| deaD | rrmJ | TOL2_C36300 | TOL2_C03430 | DeaD: cold-shock DEAD box protein; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. | RrmJ: ribosomal RNA large subunit methyltransferase J (23S rRNA methylase); Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 0.700 |
| nnrD | deaD | TOL2_C10880 | TOL2_C36300 | YjeF: uncharacterized predicted carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase [...] | DeaD: cold-shock DEAD box protein; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. | 0.765 |
| nnrD | pfaA | TOL2_C10880 | TOL2_C34430 | YjeF: uncharacterized predicted carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase [...] | PfaA: polyketide-type polyunsaturated fatty acid synthase. | 0.429 |
| nnrD | pnp | TOL2_C10880 | TOL2_C04640 | YjeF: uncharacterized predicted carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase [...] | Pnp: polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase); Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.404 |
| pfaA | deaD | TOL2_C34430 | TOL2_C36300 | PfaA: polyketide-type polyunsaturated fatty acid synthase. | DeaD: cold-shock DEAD box protein; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. | 0.710 |
| pfaA | nnrD | TOL2_C34430 | TOL2_C10880 | PfaA: polyketide-type polyunsaturated fatty acid synthase. | YjeF: uncharacterized predicted carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase [...] | 0.429 |
| pfaA | rbgA | TOL2_C34430 | TOL2_C29080 | PfaA: polyketide-type polyunsaturated fatty acid synthase. | RbgA: ribosome biogenesis GTPase; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | 0.507 |
| pfaA | rplC | TOL2_C34430 | TOL2_C34830 | PfaA: polyketide-type polyunsaturated fatty acid synthase. | RplC: 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.740 |
| pfaA | rplD | TOL2_C34430 | TOL2_C34820 | PfaA: polyketide-type polyunsaturated fatty acid synthase. | RplD: 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 0.838 |
| pfaA | rplK | TOL2_C34430 | TOL2_C34920 | PfaA: polyketide-type polyunsaturated fatty acid synthase. | RplK: 50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.776 |
| pfaA | rplM | TOL2_C34430 | TOL2_C13610 | PfaA: polyketide-type polyunsaturated fatty acid synthase. | RplM: 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.918 |
