Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
trmB-2TrmB: predicted sugar-specific transcriptional regulator. (262 aa)    
Predicted Functional Partners:
rocD
RocD: ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
       0.746
topA
TopA: DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DN [...]
   
    0.662
CCK80600.1
Putative nuclease.
   
    0.662
CCK81606.1
Putative DNA topoisomerase I.
   
    0.662
CCK80231.1
Conserved uncharacterized protein.
  
     0.522
ssb
Ssb: singel-stranded DNA-binding protein, helix-destabilizing; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
       0.507
CCK80504.1
Putative adenylate cyclase family protein.
  
     0.501
CCK82247.1
Radical SAM domain protein, related to lysine 2,3-aminomutase.
  
     0.486
prpF
PrpF: predicted 3-methylitaconate isomerase.
   
    0.484
CCK82099.1
Auxin efflux carrier; Signal peptide.
  
     0.481
Your Current Organism:
Desulfobacula toluolica
NCBI taxonomy Id: 651182
Other names: D. toluolica Tol2, Desulfobacula toluolica DSM 7467, Desulfobacula toluolica Tol2, Desulfobacula toluolica str. Tol2, Desulfobacula toluolica strain Tol2
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.