STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCK82376.1Methylenetetrahydrofolate reducatse; Belongs to the methylenetetrahydrofolate reductase family. (307 aa)    
Predicted Functional Partners:
CCK80999.1
Predicted dihydropteroate synthase.
 
 
 0.958
CCK82138.1
Fusion protein: glycine cleavage T-protein and glycine hydroxymethyltransferase.
  
 
 0.946
glyA
GlyA: serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.928
CCK78394.1
Putative thymidylate synthase.
    
 0.908
CCK82373.1
Conserved uncharacterized protein.
  
 0.848
CCK81485.1
Conserved uncharacterized protein.
  
 0.769
CCK78599.1
Conserved uncharacterized protein.
  
 0.767
CCK81392.1
Conserved uncharacterized protein.
  
 0.760
CCK80730.1
Uncharacterized protein.
  
 0.759
CCK79074.1
Conserved uncharacterized protein.
 
  
 0.748
Your Current Organism:
Desulfobacula toluolica
NCBI taxonomy Id: 651182
Other names: D. toluolica Tol2, Desulfobacula toluolica DSM 7467, Desulfobacula toluolica Tol2, Desulfobacula toluolica str. Tol2, Desulfobacula toluolica strain Tol2
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