Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tktTkt: transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (667 aa)    
Predicted Functional Partners:
talC
TalC: transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
 0.997
tpiA
TpiA: triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 0.986
rpe
Rpe: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
 
 0.984
CCK79291.1
Putative ketose-bisphosphate aldolase family protein.
  
 0.978
pgi
Pgi: glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 0.976
eno
Eno: enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 0.970
gap
Gap: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 
 0.965
prs
Prs: ribose-phosphate pyrophosphokinase (RPPK); Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 
 0.963
pyk
Pyk: pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.959
gap2
Gap2: glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 0.959
Your Current Organism:
Desulfobacula toluolica
NCBI taxonomy Id: 651182
Other names: D. toluolica Tol2, Desulfobacula toluolica DSM 7467, Desulfobacula toluolica Tol2, Desulfobacula toluolica str. Tol2, Desulfobacula toluolica strain Tol2
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