| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cbiA | cbiC | TOL2_C00080 | TOL2_C00070 | CbiA: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CbiC: precorrin-8X methylmutase. | 0.998 |
| cbiA | cbiD | TOL2_C00080 | TOL2_C00090 | CbiA: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CbiD: putative cobalt-precorrin-6A synthase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.970 |
| cbiA | cbiG | TOL2_C00080 | TOL2_C43420 | CbiA: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CbiG: cobalamin biosynthesis protein. | 0.895 |
| cbiA | cbiK | TOL2_C00080 | TOL2_C34190 | CbiA: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CbiK: sirohydrochlorin cobaltochelatase; Catalyzes the insertion of Co(2+) into sirohydrochlorin. Belongs to the CbiK family. | 0.478 |
| cbiA | cbiK2 | TOL2_C00080 | TOL2_C34310 | CbiA: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CbiK2: sirohydrochlorin cobaltochelatase; Catalyzes the insertion of Co(2+) into sirohydrochlorin. Belongs to the CbiK family. | 0.502 |
| cbiA | cbiL | TOL2_C00080 | TOL2_C43380 | CbiA: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CbiL: cobalt-precorrin-2 C(20)-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.905 |
| cbiA | cobJ | TOL2_C00080 | TOL2_C43430 | CbiA: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CobJ: precorrin-3B C(17)-methyltransferase. | 0.869 |
| cbiA | cobL | TOL2_C00080 | TOL2_C43400 | CbiA: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CobL: precorrin-6Y C(5,15)-methyltransferase. | 0.921 |
| cbiA | cobM | TOL2_C00080 | TOL2_C43410 | CbiA: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CobM: precorrin-4 C(11)-methyltransderase; Belongs to the precorrin methyltransferase family. | 0.892 |
| cbiA | cobQ | TOL2_C00080 | TOL2_C43450 | CbiA: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CobQ: cobyrinic acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.968 |
| cbiC | cbiA | TOL2_C00070 | TOL2_C00080 | CbiC: precorrin-8X methylmutase. | CbiA: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.998 |
| cbiC | cbiD | TOL2_C00070 | TOL2_C00090 | CbiC: precorrin-8X methylmutase. | CbiD: putative cobalt-precorrin-6A synthase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.993 |
| cbiC | cbiG | TOL2_C00070 | TOL2_C43420 | CbiC: precorrin-8X methylmutase. | CbiG: cobalamin biosynthesis protein. | 0.975 |
| cbiC | cbiK | TOL2_C00070 | TOL2_C34190 | CbiC: precorrin-8X methylmutase. | CbiK: sirohydrochlorin cobaltochelatase; Catalyzes the insertion of Co(2+) into sirohydrochlorin. Belongs to the CbiK family. | 0.839 |
| cbiC | cbiK2 | TOL2_C00070 | TOL2_C34310 | CbiC: precorrin-8X methylmutase. | CbiK2: sirohydrochlorin cobaltochelatase; Catalyzes the insertion of Co(2+) into sirohydrochlorin. Belongs to the CbiK family. | 0.842 |
| cbiC | cbiL | TOL2_C00070 | TOL2_C43380 | CbiC: precorrin-8X methylmutase. | CbiL: cobalt-precorrin-2 C(20)-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.985 |
| cbiC | cobJ | TOL2_C00070 | TOL2_C43430 | CbiC: precorrin-8X methylmutase. | CobJ: precorrin-3B C(17)-methyltransferase. | 0.995 |
| cbiC | cobL | TOL2_C00070 | TOL2_C43400 | CbiC: precorrin-8X methylmutase. | CobL: precorrin-6Y C(5,15)-methyltransferase. | 0.998 |
| cbiC | cobM | TOL2_C00070 | TOL2_C43410 | CbiC: precorrin-8X methylmutase. | CobM: precorrin-4 C(11)-methyltransderase; Belongs to the precorrin methyltransferase family. | 0.985 |
| cbiC | cobQ | TOL2_C00070 | TOL2_C43450 | CbiC: precorrin-8X methylmutase. | CobQ: cobyrinic acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.993 |