| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cbiA | cbiB | TOL2_C00080 | TOL2_C39900 | CbiA: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CbiB: cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.911 |
| cbiA | cbiC | TOL2_C00080 | TOL2_C00070 | CbiA: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CbiC: precorrin-8X methylmutase. | 0.998 |
| cbiA | cbiD | TOL2_C00080 | TOL2_C00090 | CbiA: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CbiD: putative cobalt-precorrin-6A synthase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.970 |
| cbiA | cbiG | TOL2_C00080 | TOL2_C43420 | CbiA: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CbiG: cobalamin biosynthesis protein. | 0.895 |
| cbiA | cbiL | TOL2_C00080 | TOL2_C43380 | CbiA: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CbiL: cobalt-precorrin-2 C(20)-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.905 |
| cbiA | cobJ | TOL2_C00080 | TOL2_C43430 | CbiA: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CobJ: precorrin-3B C(17)-methyltransferase. | 0.869 |
| cbiA | cobL | TOL2_C00080 | TOL2_C43400 | CbiA: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CobL: precorrin-6Y C(5,15)-methyltransferase. | 0.921 |
| cbiA | cobM | TOL2_C00080 | TOL2_C43410 | CbiA: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CobM: precorrin-4 C(11)-methyltransderase; Belongs to the precorrin methyltransferase family. | 0.892 |
| cbiA | cobQ | TOL2_C00080 | TOL2_C43450 | CbiA: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CobQ: cobyrinic acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.968 |
| cbiA | cobS | TOL2_C00080 | TOL2_C39880 | CbiA: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CobS: cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.730 |
| cbiB | cbiA | TOL2_C39900 | TOL2_C00080 | CbiB: cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | CbiA: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.911 |
| cbiB | cbiC | TOL2_C39900 | TOL2_C00070 | CbiB: cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | CbiC: precorrin-8X methylmutase. | 0.914 |
| cbiB | cbiD | TOL2_C39900 | TOL2_C00090 | CbiB: cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | CbiD: putative cobalt-precorrin-6A synthase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.805 |
| cbiB | cbiG | TOL2_C39900 | TOL2_C43420 | CbiB: cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | CbiG: cobalamin biosynthesis protein. | 0.818 |
| cbiB | cbiL | TOL2_C39900 | TOL2_C43380 | CbiB: cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | CbiL: cobalt-precorrin-2 C(20)-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.810 |
| cbiB | cobJ | TOL2_C39900 | TOL2_C43430 | CbiB: cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | CobJ: precorrin-3B C(17)-methyltransferase. | 0.875 |
| cbiB | cobL | TOL2_C39900 | TOL2_C43400 | CbiB: cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | CobL: precorrin-6Y C(5,15)-methyltransferase. | 0.893 |
| cbiB | cobM | TOL2_C39900 | TOL2_C43410 | CbiB: cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | CobM: precorrin-4 C(11)-methyltransderase; Belongs to the precorrin methyltransferase family. | 0.837 |
| cbiB | cobQ | TOL2_C39900 | TOL2_C43450 | CbiB: cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | CobQ: cobyrinic acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.994 |
| cbiB | cobS | TOL2_C39900 | TOL2_C39880 | CbiB: cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | CobS: cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.980 |