| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cbiA | cbiB | TOL2_C00080 | TOL2_C39900 | CbiA: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CbiB: cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.911 |
| cbiA | cbiC | TOL2_C00080 | TOL2_C00070 | CbiA: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CbiC: precorrin-8X methylmutase. | 0.998 |
| cbiA | cbiL | TOL2_C00080 | TOL2_C43380 | CbiA: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CbiL: cobalt-precorrin-2 C(20)-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.905 |
| cbiA | cobB | TOL2_C00080 | TOL2_C05600 | CbiA: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CobB: cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.914 |
| cbiA | cobD | TOL2_C00080 | TOL2_C39890 | CbiA: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CobD: threonine-phosphate decarboxylase. | 0.830 |
| cbiA | cobJ | TOL2_C00080 | TOL2_C43430 | CbiA: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CobJ: precorrin-3B C(17)-methyltransferase. | 0.869 |
| cbiA | cobM | TOL2_C00080 | TOL2_C43410 | CbiA: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CobM: precorrin-4 C(11)-methyltransderase; Belongs to the precorrin methyltransferase family. | 0.892 |
| cbiA | cobO | TOL2_C00080 | TOL2_C43440 | CbiA: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CobO: cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.946 |
| cbiA | cobQ | TOL2_C00080 | TOL2_C43450 | CbiA: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CobQ: cobyrinic acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.968 |
| cbiA | cobU | TOL2_C00080 | TOL2_C39860 | CbiA: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CobU: predicted bifunctional adenosylcobalamin biosynthesis protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.856 |
| cbiB | cbiA | TOL2_C39900 | TOL2_C00080 | CbiB: cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | CbiA: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.911 |
| cbiB | cbiC | TOL2_C39900 | TOL2_C00070 | CbiB: cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | CbiC: precorrin-8X methylmutase. | 0.914 |
| cbiB | cbiL | TOL2_C39900 | TOL2_C43380 | CbiB: cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | CbiL: cobalt-precorrin-2 C(20)-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.810 |
| cbiB | cobB | TOL2_C39900 | TOL2_C05600 | CbiB: cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | CobB: cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.875 |
| cbiB | cobD | TOL2_C39900 | TOL2_C39890 | CbiB: cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | CobD: threonine-phosphate decarboxylase. | 0.998 |
| cbiB | cobJ | TOL2_C39900 | TOL2_C43430 | CbiB: cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | CobJ: precorrin-3B C(17)-methyltransferase. | 0.875 |
| cbiB | cobM | TOL2_C39900 | TOL2_C43410 | CbiB: cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | CobM: precorrin-4 C(11)-methyltransderase; Belongs to the precorrin methyltransferase family. | 0.837 |
| cbiB | cobO | TOL2_C39900 | TOL2_C43440 | CbiB: cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | CobO: cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.978 |
| cbiB | cobQ | TOL2_C39900 | TOL2_C43450 | CbiB: cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | CobQ: cobyrinic acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.994 |
| cbiB | cobU | TOL2_C39900 | TOL2_C39860 | CbiB: cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | CobU: predicted bifunctional adenosylcobalamin biosynthesis protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.995 |