STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadENAD+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (714 aa)    
Predicted Functional Partners:
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.943
nadK
NAD+ kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
    
 0.938
cobB
NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily.
    
 0.936
SKB46556.1
Glutamate synthase (NADPH/NADH) large chain.
    
 0.934
SKC15182.1
Hypothetical protein.
  
 
 0.918
SKB73450.1
Allosteric NADP-dependent malic enzyme.
    
  0.914
SKB55842.1
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
 
 
 0.876
SKB73227.1
ADP-ribose pyrophosphatase YjhB, NUDIX family; Belongs to the Nudix hydrolase family.
 
  
 0.865
SKC19431.1
Protein of unknown function.
    
 0.840
SKC06898.1
Nicotinamide-nucleotide amidase; Belongs to the CinA family.
    
 0.834
Your Current Organism:
Dyadobacter psychrophilus
NCBI taxonomy Id: 651661
Other names: CGMCC 1.8951, D. psychrophilus, DSM 22270, Dyadobacter psychrophilus Zhang et al. 2010, Dyadobacter sp. BZ26, strain BZ26
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.